The Low-Coste Innovation Blog welcomes YOU

Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!

Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.

After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". My name's Catherine Coste. I've earned myself two MIT digital diplomas: 7.00x and 7QBWx. Instructor: Eric Lander PhD.

My motto: Go Where You Are Celebrated, Not Where You Are Tolerated.

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC ( to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (

Appel à témoignage - Please share your experience - Teilen Sie Ihre Erfahrungen mit ! Don d'organes - Organ Donation - Organspende :

Appel à témoignage : lettre ouverte aux proches confrontés à la question du don d'organes (lire)

Please share your experience : letter to the attention of next-of-kin of donor-eligible individuals (read)

Im Krankenhaus oder in der Klinik wurden Sie nach dem mutmasslichen Willen Ihres Verwandten gefragt : ob er oder sie sich für Organspende ausgesprochen habe. Bitte teilen Sie Ihre Erfahrung mit ! (lesen)

Avertissement :

Merci de ne PAS poster de messages concernant la vente d'un organe et comportant des coordonnées téléphoniques, e-mail, etc. La loi française interdit la vente d'organes.


"Doctors wanted to extend life. Instead they extended death"

Find the author of this blog on LinkedIn

Highly interested in precision "genomic" medicine, in mHealth and patient engagement. MOOC & book worm. Earned myself two MITx edX certificates: genomics and python (quantitative medicine).

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The one thing you need to know about me: passionate about science and society, working on a writing project: genomic entertainment. From the Broad Institute to Broadway? I'm talking about the human genome project here -- so YES: I'm talking about YOUR own genome...

I did a post-graduate teacher training at La Sorbonne university, Paris, taught German language and literature in middle and high school for over a decade and earned myself two MITx EdX digital diplomas (certificates) in genomics and quantitative biology: 7000x and 7.QBWx. Currently a MOOC student: "Explore Statistics With R" (edX). One last thing: I am a writer.

My message to Regina Holliday -- The Walking Gallery Of Patients (sent 08/18/2014):

"Faites sauter la banque"

"$1 million prize incentive to create an artificial liver!"

Using MinION sequencing machine, sitting at my kitchen table...

... like so:
"One scientist this month tweeted a picture of the sequencer on his dining room table, decoding DNA."

Having your genome sequenced at your own request or initiative is forbidden by law in France. L.O.L.

"David Deamer made this sketch in 1989 when the idea for nanopore sequencing came to him. One day in 1989, biophysicist David Deamer pulled his car off California’s Interstate 5 to hurriedly scribble down an idea. In a mental flash, he had pictured a strand of DNA threading its way through a microscopic pore. Grabbing a pen and a yellow pad, he sketched out a radical new way to study the molecule of life. Twenty-five years later, the idea is now being commercialized as a gene sequencing machine that’s no larger than a smartphone, and whose effects might eventually be similarly transformative." Source.