Precision Medicine will need to get out of the pharma silo that is based on symptoms

Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!

Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.

After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Doomsdare, a medical thriller (action taking place in Beijing) June 2016; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (Nov. 2016). My other half in writing is Isabelle Provost, we have been writing together since 2009.

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC ( to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (

Upcoming books 2016

Using Stem Cells To Reactivate The Brains Of The Dead?

Welcome. I'm a Freelance Journalist and a Networking Jedi

Dying Steve Jobs: "Biology and I.T. have merged." Time to learn about it.
Freelance journalist. Personal Genomics Advocate with strong social media skills.
Find me on Twitter, LinkedIn, Facebook.

Upcoming books (2016):
Doomsdare -- medical thriller (in 2 volumes).
Jesus CRISPR Superstar -- sci-fi.
Publishing house: British (Oxford, UK)

Disneyland Paris, Oct. 2014
Australia, January 2016
Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.

2016: Fun MOOC - Institut Catholique de Paris (ICP) "Géopolitique de la Chine Contemporaine", by Prof. Emmanuel Lincot. 97% total score.

2015-2016: MIT - edX digital diploma Molecular Biology – Part 1: 7.28.1x "DNA Replication & Repair" (76% TOTAL SCORE), 7.28.2x Molecular Biology – Part 2: Transcription and Transposition (81 % TOTAL SCORE).

2013 - 2014: MIT - edX digital diplomas: 7.00x "The Secret of Life" (76% TOTAL SCORE) & 7.QBWx "Quantitative Biology Workshop" (90% TOTAL SCORE).

All things genomics.
Science = Perpetual Ascension.
Sci-fi writer: From the Broad Institute to Broadway?
Science & Society, Genomic Entertainment.

I graduated in German literature. Post-graduate teacher training at La Sorbonne University, Paris (1997/1998, 2006/2007). Master's degree in social market economy and traductology. As an undergraduate, I studied linguistics and didactics.
Work: sales & marketing assistant; middle & high school teacher, blogger.
Co-founder of the Atelier e-santé (France) with Jean-Michel Billaut.
MITx-EdX 7.00x, 7.28x, 7.28.1x certified. Genomics & Python.

Find me on Twitter @ #PWSYN - "The Patient Will See You Now", 2015 Medical Bestseller by Eric Topol MD.


But I've seen a lot of hubris in the field of organ transplant, where "generosity" is being used and abused as keyword...

My 8 followers on Weibo (Chinese equivalent of Twitter)

Really love this one!
Have signed with an Oxford UK publishing house a contract for 3 fictions, which should all be out before April 2017.

Doomsdare, a medical thriller (action taking place in Beijing)
Jesus CRISPR Superstar, a sci-fi, written with Isabelle Provost
French version of the sci-fi: La Passion Du CRISPR.

Then, from April 2017 on, will spend one year in Asia, emphasis on China. My very recent stays in Beijing? A shock, an ongoing one, one foot in fairy tale (thank you Cixin Liu) one foot in abyss (hashtag airpocalypse). Have seen a few things about the development of mHealth in China and want to explore... Thank you Jean-Michel Billaut (French blogger) for the tutorial sessions that should help me find ways to monetize those stays in Asia...

My (modest) mHealth Silk Road (LOL) project: Will explore startup incubators in Malaysia (Cyberjaya), North of Thailand and various parts of China from April to (at least) December 2017...

Have a passion for Chinese language and civilization anyway...

Of course, will attend mHealth congresses in China wearing Regina Holliday's jacket -- the one she painted for me... Chinese people usually love this jacket (from what I saw on a couple of opportunities in Beijing and Shanghai)...

8 followers on Weibo already, including Veritas Genetics (Shanghai), hopefully soon 12...

ICP Géopolitique Chine Contemporaine

Another MOOC I've just completed. Great one... (in French). Thank you so much Professeur Emmanuel Lincot, Institut Catholique de Paris.

You, Your Data, Your Genome

Portable Genomics is a startup in San Diego, California.

Want to know what is at the forefront of digital medicine? Your genome on your mobile, since biology is going digital, is something that is bound to happen...

Read Portable Genomics' Press Release (hot off the press)!

Courtesy of Patrick Merel, Founder of Portable Genomics:

Download PDF here: link.

Heart Haiku

What could a Doctor from the future say about (for ex.) heart transplants? Have a Bone(s) to pick with organ transplants?... This is all fiction, of course... I guess a doctor from the future would find this obsession with vital organs (conventional medicine is an organ-based science; not a science based on the cell(s), the molecules and even individual atoms) weird and scientifically inaccurate.

Don't replace my heart
With a stethoscope.

I carry your heart
With me
A two-faced story.

Carved in the story
Of organ transplant.

I carry your heart...
Agape / Eros
Beat in unison
Fight in unison

Life and death story
Yes. Tim Burton style.

Don't replace my heart
With a stethoscope.

Reading, Writing and Mangas

Reading (if you don't read, you don't write, right?)

Awesome book, discussing it with engineers in my network /guanxi
Also, see:

And I've just received this one:

Also, found this old book I've been reading and studying a loooong time ago at La Sorbonne (Germanistik)

... and watching a lot of Mangas... a bit of everything, actually... Is my brain storing every fact, info or piece of narrative I chance upon in manga-style and format? I'm afraid it might.