Precision Medicine will need to get out of the pharma silo that is based on symptoms

Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!

Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.

After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself three MIT digital diplomas: 7.00x, 7.28x1 and 7QBWx. Instructor of 7.00x: Eric Lander PhD. 7.28.x2 student.

My motto: Go Where You Are Celebrated, Not Where You Are Tolerated.

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC ( to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (

Appel à témoignage - Please share your experience - Teilen Sie Ihre Erfahrungen mit ! Don d'organes - Organ Donation - Organspende :

Appel à témoignage : lettre ouverte aux proches confrontés à la question du don d'organes (lire)

Please share your experience : letter to the attention of next-of-kin of donor-eligible individuals (read)

Im Krankenhaus oder in der Klinik wurden Sie nach dem mutmasslichen Willen Ihres Verwandten gefragt : ob er oder sie sich für Organspende ausgesprochen habe. Bitte teilen Sie Ihre Erfahrung mit ! (lesen)

Avertissement :

Merci de ne PAS poster de messages concernant la vente d'un organe et comportant des coordonnées téléphoniques, e-mail, etc. La loi française interdit la vente d'organes.


Mein Lieblingsgedicht

Health Care activist Regina Holliday usually asks the people she gets to meet: "What is your favorite fairy tale?" I tend to ask people: "What is your favorite poem?"

Here is mine (btw I am a German native speaker).

Nur zwei Dinge


Durch so viele Formen geschritten,
durch Ich und Wir und Du,
doch alles blieb erlitten
durch die ewige Frage: wozu? Das ist eine Kinderfrage.
Dir wurde erst spät bewußt,
es gibt nur eines: ertrage
- ob Sinn, ob Sucht, ob Sage-
dein fernbestimmtes: Du mußt.
Ob Rosen, ob Schnee, ob Meere,
was alles erblühte, verblich,
es gibt nur zwei Dinge: die Leere
und das gezeichnete Ich. 

Gottfried Benn (Arzt: Dermatolog, Dichter)

Welcome. I'm a Freelance Journalist and a Networking Jedi

Dying Steve Jobs: "Biology and I.T. have merged." Time to learn about it.
Freelance journalist. Personal Genomics Advocate with strong social media skills.
Find me on Twitter, LinkedIn, Facebook.

Disneyland Paris, Oct. 2014
Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.

2015-2016: MIT - edX digital diploma 7.28.1x "DNA Replication & Repair" (76% TOTAL SCORE). Working on 7.28.2x.

2013 - 2014: MIT - edX digital diplomas: 7.00x "The Secret of Life" (76% TOTAL SCORE) & 7.QBWx "Quantitative Biology Workshop" (90% TOTAL SCORE).

All things genomics.
Science = Perpetual Ascension.
Sci-fi writer: From the Broad Institute to Broadway?
Science & Society, Genomic Entertainment.

I graduated in German literature. Post-graduate teacher training at La Sorbonne University, Paris (1997/1998, 2006/2007). Master's degree in social market economy and traductology. As an undergraduate, I studied linguistics and didactics.
Work: sales & marketing assistant; middle & high school teacher, blogger.
Co-founder of the Atelier e-santé (France) with Jean-Michel Billaut.
MITx-EdX 7.00x, 7.28x, 7.28.1x certified. Genomics & Python.

Find me on Twitter @ #PWSYN - "The Patient Will See You Now", 2015 Medical Bestseller by Eric Topol MD.

RoboHumanity and the Skinny Love Virus Projection

RoboHumanity and the Skinny Love Virus Projection

Picture by Lithuanian artist Natalie Shau

"Thing Explainer: Complicated Stuff in Simple Words"
The next must-read book on my list...

"No religion will ever be able to stop this"

A picture of me that means a lot to me.
Found it digging in the archives of this blog...
I am in Malaysia, this is May 2011 and I am trying to pray (buddhist style) for the victims of organ trafficking in China. I had to convince the lady in the temple to let me perform this religious ritual as I told her I was acting on behalf of families of dead Chinese prisoners. If you are hungry for the gruesome details, read "Bloody Harvest" by my friend David Kilgour and his colleague, Canadian lawyer David Matas (you'll be sorry you asked). There was really a lot of smoke in there (I can't see it on the picture, but I do recall it) and plenty of monkeys right next to the entrance of this cave (the temple is actually a cave) located in the mountain. "The monkeys are my bodyguards," so I told half jokingly the lady, since my Chinese astrological sign is earth monkey. I was lucky the lady could speak Mandarin Chinese (she didn't speak English), since Cantonese Chinese speakers are very frequent in Malaysia, but Mandarin... not so much. She looked as I performed my "ritual". This is probably the only time in my life I really tried to pray, ironically this was in a religious language I was not at all familiar with: buddhism. When I was done she poured me some tea, like she was Sheldon Cooper in Big Bang Theory, offering Bernadette (Soubirous, that lady of Lourdes Caves in France) a hot beverage. She commented in a sad voice (kind of talking to herself): "No religion will ever be able to stop this".

I really hope that cool CRISPR-Cas 9 genome editing tool will work, sooner than later. Spoke with my friend David Kilgour today. Those atrocities are still going on...

The Truth Lies Somewhere In The Middle

Eric Topol MD's twitter account Nov. 22 2015

The Mammon Doctor Will See You Now?! I prefer the #PWSYN book to this pic -> not representative of the book.

In Memoriam...

Ne cherchez pas les mots pour expliquer ce qui s'est passé, il n'y en a pas. Mais il vous faudra chercher les mots, longtemps, souvent et sur bien des routes différentes, pour continuer à vivre.