Precision Medicine will need to get out of the pharma silo that is based on symptoms
Welcome to the digital era of biology (and to this modest blog I started in early 2005).
To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!
Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.
After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.
My motto: Go Where You Are Celebrated, Not Where You Are Tolerated.
I love Genomics. Would you rather donate your data, or... your vital organs?
Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.
Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).
|At Beijing airport, Jan. 2016|
Writing a medical
#thriller, the action is taking place in China. Will be out this year. Will be dedicated to Canadian #lawyer David Kilgour
“We are rewriting the pig genome for organ transplantation,” says @JCVenter https://t.co/OAPHl7QIin @mosaicscience pic.twitter.com/zi9RpnjkGc— CATHERINE COSTE (@cathcoste) February 3, 2016
|Great article on the future of organ transplant and religion by MIT Tech Review's Antonio Regalado:|
Pope Francis Said to Endorse Human-Animal Mixtures https://t.co/7IkajasbSV— Antonio Regalado (@antonioregalado) January 27, 2016
Salk scientist says Pope blessed his human-animal chimeras. https://t.co/MITFoO04tq Background: https://t.co/hD1lywuPY5 h/t: @cells_nnm— Antonio Regalado (@antonioregalado) January 26, 2016
|Dying Steve Jobs: "Biology and I.T. have merged." Time to learn about it.|
Find me on Twitter, LinkedIn, Facebook.
|Disneyland Paris, Oct. 2014|
|Australia, January 2016|
2015-2016: MIT - edX digital diploma Molecular Biology – Part 1: 7.28.1x "DNA Replication & Repair" (76% TOTAL SCORE), 7.28.2x Molecular Biology – Part 2: Transcription and Transposition (81 % TOTAL SCORE).
2013 - 2014: MIT - edX digital diplomas: 7.00x "The Secret of Life" (76% TOTAL SCORE) & 7.QBWx "Quantitative Biology Workshop" (90% TOTAL SCORE).
All things genomics.
Science = Perpetual Ascension.
Sci-fi writer: From the Broad Institute to Broadway?
Science & Society, Genomic Entertainment.
I graduated in German literature. Post-graduate teacher training at La Sorbonne University, Paris (1997/1998, 2006/2007). Master's degree in social market economy and traductology. As an undergraduate, I studied linguistics and didactics.
Work: sales & marketing assistant; middle & high school teacher, blogger.
Co-founder of the Atelier e-santé (France) with Jean-Michel Billaut.
MITx-EdX 7.00x, 7.28x, 7.28.1x certified. Genomics & Python.
|Find me on Twitter @ #PWSYN - "The Patient Will See You Now", 2015 Medical Bestseller by Eric Topol MD.|
I am a networking Jedi & this is my Exponential Connection laser gizmo, by @ReginaHolliday http://t.co/K1dl0ez2O4 pic.twitter.com/MAgDhzZDli— CATHERINE COSTE (@cathcoste) June 28, 2015
In @FLGenomics Mag., I wrote about #healthcare being disrupted by Moore's Law #PWSYN @MITxBio http://t.co/23LgeQkS3A pic.twitter.com/XqT7zT3jHj— CATHERINE COSTE (@cathcoste) August 10, 2015
#PrecisionMedicine has incredible potential to protect transplant patients. Catch Dr. Sarwal today at noon. #PMWC16 pic.twitter.com/HUVTRT9sQ1— UC San Francisco (@UCSF) January 25, 2016
Scientists from Australia & UK have created a “biosensor mouse” that predicts spread of pancreatic cancer cells https://t.co/SxgnGBSh7O
— GNN Good News (@GNNGoodNews) January 6, 2016If dying Steve Jobs
And Andrew Lloyd Webber
Wrote a Musicome
"Aren't you tired of all those
It would tell the story
Of that cool genome
Who is this Jesus CRISPr?
With a sick son
Get a Nobel Prize.
"Cracking the Code"
"Fixing the Code"
All done by parents:
The Mission Massimo team.
Nobody else seems
to be in charge.
Not even doctors
Not even scientists
Not even academia
Not even big pharma.
Mission Massimo was crazy.
But at M.I.T.
I was told that
"Crazy" could earn you a Nobel Prize
Even if you have no PhD
But end up
Jesus CRISPr and Mission Massimo
Did some disease modeling on a mouse
Then they built a platform
To cure thousands of people.
Three decades later
Old Mission Massimo
Steals the show.
Jesus CRISPr Superstar
Sharing a Nobel Prize
With the crazy people.
A big day for genome editing & hope in muscular dystrophy: #CRISPR corrects in mouse model https://t.co/9B8d5kXzbe pic.twitter.com/DaTB0QS7r6— Eric Topol (@EricTopol) December 31, 2015
Just wrote my review of #CrackingTheCode in German on @Amazon https://t.co/WrJ9OwsXbz cc @missionmassimo @leahkam pic.twitter.com/YyHS6EpUEa— CATHERINE COSTE (@cathcoste) January 2, 2016
Jesus #CRISPR Superstar, a remake of Lloyd Webber #musical, w/ @MIT stars @eric_lander @zhangf. Superstar: bacteria. https://t.co/03fumRxh77— CATHERINE COSTE (@cathcoste) January 21, 2016
Controversial CRISPR history sets off an online firestorm! More interesting than Amy awards or RealityTV storms... https://t.co/1JdZlxFk5U— Guillaume Plane (@GuillaumePlane) January 20, 2016
Hoping that #CRISPR patent battle will not be a remake of the War of Currents with Thomas Edison VS Nikola Tesla - https://t.co/aWhlx0wufh— CATHERINE COSTE (@cathcoste) January 23, 2016
.@EricTopol Hoping that #CRISPR legal war won't be a remake of the War of Currents with Thomas Edison VS Nikola Tesla #lawyerswillgetricher— CATHERINE COSTE (@cathcoste) January 24, 2016
This biotech company is trying to make a rare disease drug cheaper. Will it work? https://t.co/O3ufrf6bwn pic.twitter.com/ZKAZcAuZVs— STAT (@statnews) 24 Janvier 2016
Interesting CRISPR history https://t.co/HsVJrFd6Ud The seminal observations were rejected in every high-IF journal! pic.twitter.com/cnmT9zXAhT— Victor de Lorenzo (@vdlorenzo_CNB) January 15, 2016
.@KellyLaMarco @broadinstitute Also a rare form of patient activism #raredisease https://t.co/8dA1D96vrI @leahkam pic.twitter.com/yXEHAXusKo— CATHERINE COSTE (@cathcoste) January 25, 2016
The videos from this course are useful for a #scifi writer :-) #Programing #EricGrimson #Python #MIT #6001x @cp92isa https://t.co/1ogwoQcMJ0— CATHERINE COSTE (@cathcoste) January 25, 2016
Intro to Computer Science & #Programming starts today! Learn a new skill in the new year: https://t.co/Lk5X0UIHwA pic.twitter.com/1MaQc40fzb— MITx on edX (@MITxonedX) January 13, 2016
Creating #biologic #medicines is a complex process comprised of four main steps. https://t.co/RQpLWxE4Rw— Amgen Biosimilars (@AmgenBiosim) January 19, 2016
Lander's message to Broad Institute regarding "Heroes of Crispr" conflagration. pic.twitter.com/wPe99QhIri— Antonio Regalado (@antonioregalado) January 29, 2016
This is me. Still struggling to find some kind of comfort zone. Any comfort zone would do, I am neither picky nor fussy... But I can't seem to get there, as I keep falling into those bloody holes... Meanwhile, time is ticking...
|Should I start looking for my ancestors and my genetic profile? |
23andMe, what do you make of this??...