The Low-Coste Innovation Blog welcomes YOU

Welcome to this modest blog I started in early 2005!

To cure many diseases, like cancer or cystic fibrosis, we will need to target gene mutations, not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome).
Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.

After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG".

Jean-Michel Billaut, famous French @nthropologist and Net economy geek : "
There are times when I think there are basically two kinds of people in my country ... A '1.0' Top-Management, frantically clinging to and stuck in the past and in (bio)conservatism... and a '2.0' startup ecosystem... building... building slowly... towards the future..."

Catherine Coste,
MIT certificate in Genomics, a Tim Burton fan (whose films are dealing with death, like this modest Blog -- and sometimes we just hate it!), a Wellywood fan (the new Hollywood)... I come from France (hopefully from that "2.0" part thing) and travel a lot: New-Zealand, Asia (Malaysia, Singapore), UK...

A death and health geek and travel buff of some kind, I love meeting new faces
. My motto:
Go Where You Are Celebrated, Not Where You Are Tolerated.

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC ( to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (

Appel à témoignage - Please share your experience - Teilen Sie Ihre Erfahrungen mit ! Don d'organes - Organ Donation - Organspende :

Appel à témoignage : lettre ouverte aux proches confrontés à la question du don d'organes (lire)

Please share your experience : letter to the attention of next-of-kin of donor-eligible individuals (read)

Im Krankenhaus oder in der Klinik wurden Sie nach dem mutmasslichen Willen Ihres Verwandten gefragt : ob er oder sie sich für Organspende ausgesprochen habe. Bitte teilen Sie Ihre Erfahrung mit ! (lesen)

Avertissement :

Merci de ne PAS poster de messages concernant la vente d'un organe et comportant des coordonnées téléphoniques, e-mail, etc. La loi française interdit la vente d'organes.


Not a scientist? Become one in four months with MIT 7.00x MOOC: "The Secret of Life", starting June 17, 2014. Enrol now, it's free!

MIT MOOC 7.00x "The Secret of Life"?! What's that?? To answer your question, here's the best read I was able to find:
This course will be live in June 2014! Enrol now!

Now, about my own experience: becoming gene savvy in four months?! How do you do that?

Healthcare consumers will need to become increasingly savvy regarding their genes...

Not a scientist? Become one in four months with MIT 7.00x MOOC: "The Secret of Life"
 (PDF Doc, 4 pages).

==> Software Tools that are being used for MIT Genomics courses: see here

Amazing!! With the help of this really "Awesome Sreenshot" software, I've been able to print each and every screen/page, with all the problem sets and midterm and final exams, including correction! 101 documents that will come in handy whenever I will feel like I need to review some or all of this stuff that gave me so much fun and challenge -- and that I came to love ;-)

Genomic and Precision Medicine: UCSF MOOC (started April 14, 2014)

"San Diego heart of digital health innovation"


People who impress me most:
Jack Andraka, Ray Kurzweil, Eric Topol, Maurice Béjart.

People who changed my life:
Steve Jobs, geneticist and MIT Professor Eric Lander PhD.

My favorite music:

My favorite book (2014):  
J. Craig Venter: "Life at the speed of light".

Favorite writer: Jasper Fforde, a Fantasy/SF/Comedy/Crime author who lives in Wales. 

As I love genomics and musicals, I'm trying to merge both... Monster High Institute of Tech is hitting Growlway: ever heard of the ughsome clawsome MIT Salem genomic musical?

MIT edX Certification in Genomics obtained 18/12/2013. Professor: Eric Lander PhD. I'm a Personal Genomics Advocate with strong social media skills, a Semantic Web Geek and a Web Science Evangelist.

Exploring personal genomics involves dedicated microchips. Navigating their own genome on their iPhone, thanks to an "app" that will show a list of variants that can be tailored to the patients' genomic data, and with the help of their physician, patients will be able to become the Risk Manager of their own genome... And oh, yes, of course, we will need to have those FDA guys on board!

To cure diseases like cancer and cystic fibrosis, we will need to target gene mutations; not organs.

Catherine Coste in 3 words: I SELL IDEAS! I LOVE GENOMICS.

Looking for Marketing ideas from London to Singapore!? Look no further!

Passionate about excellence in science (= Perpetual Ascension). Committed to excellence in writing. Scientific + Creative Writing = Marketing.

English, German, French & Basic oral Mandarin Chinese... My family lives in Malaysia (plenty of opportunities for me to improve my Mandarin Chinese), in NY & in Germany -- I'm a German native speaker.

OK, OK, now you're hooked, keep reading.....

A health geek and travel buff, I love meeting new faces. People around me say I'm all about creativity and marketing, new ideas and sustainable everything.

My 2014 favorite book: "Damn Good Advice (for people with talent!)" by George Lois.
I'm a Robin Cook and Tim Burton fan.
Science and society: genomic entertainment.
LinkedIn Page here.
Facebook Wall here.
Twitter Account here.
Singularity Hub

"A transplant is not a cure": my letter to Steve Jobs.

2013: MOOC student, registered for the course MITx: The Secret of Life, Intro to Biology, by Eric Lander, PhD.  

Follow me on Twitter:  

"IBM's Watson Supercomputer May Soon Be The Best Doctor In The World"

Puttin On The Ritz - Irving Berlin - Pomplamoose

"Genome Sequencing Brings Hope to La Jolla Teen"

Every time I get to see Lilly Grossman's compelling story and updates on the net -- loved her book: "The girl they thought they never knew", by the way -- I get... slightly emotional. I admire her a lot -- her and her family. They are truly extraordinary people. Inspiring. As a genomic geek, I DO hope that Lilly's condition will be improved thanks to precision (genomic) medicine. My heart goes out to this family... Go Lilly!!!!!!!!!

A big fan of yours :-)

"Print your own 50-cent microscope - Retraction of Malaria"

"Homo innovaticus"

Massimo Banzi's key note at "The First Day of Tomorrow", Paris, April 18 - 2014

The First Day of Tomorrow Conference in Paris - April 18, 2014


The First Day of Tomorrow Conference in Paris - April 18, 2014:

==> a few snapshots

Many thanks to Xavier Duportet for making this (slightly disruptive) event come true in Paris! Oh, and you might wanna check on Twitter...
And the winner is...

No doubt the IBM Watson will be interested in Google Deep Mind (and vice-versa)...