Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Doomsdare, a medical thriller (action taking place in Beijing) Fall 2016; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2017). Special thanks to Prof. Emmanuel Lincot, lawyer David Kilgour and Isabelle Provost for their help.

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


"The world loses one child per minute due to malaria". QuantuMDx: Crowdfunding Malaria DNA Testing

"'Our Crowdfunding campaign is unique,' explained Elaine Warburton, OBE, CEO of QuantuMDx, in a press release. 'Not only are we looking for contributors to support this phenomenally worthy cause to help save many hundreds if not thousands of children’s lives, but we’re also offering everyone the chance to leave a lasting legacy in the fight against malaria by contributing their winning ideas to the look and feel of our device and to take part in re-naming it from the current research name of Q-POC.'
According to the press release, the world loses one child per minute due to malaria. The impact of a handheld DNA testing assay without the need for clean water or a stable electricity source could make all the difference in developing nations and countries in need. The funds rasied via Indiegogo will go towards further development and the effort to expand clinical trials for the new technology.
'We have spent years developing our tech and we now have a prototype device that has completed a sample-to-result malaria DNA test in under 15 minutes,' said Jonathan O’Holleran, CSO of QuantuMDx and inventor of their signature handheld assay, in the press release. 'Contributions will help take our life-saving device from the lab to the field and directly save lives. We have health workers around the world crying out for our technology and are now receiving the support of major MGOs, we just need help to finalize our development and drive the technology through clinical trials.'"

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