Precision Medicine will need to get out of the pharma silo that is based on symptoms

Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!

Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.

After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Doomsdare, a medical thriller (action taking place in Beijing) Fall 2016; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2017). Special thanks to Prof. Emmanuel Lincot, lawyer David Kilgour and Isabelle Provost for their help.

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC ( to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (

Blogs ou sites "coup de coeur"

"Juste après dresseuse d'ours" : blog d'une jeune généraliste

"Le Fils du Dr. Sachs"

Le blog de David Di Nota, écrivain (Gallimard) :

Une BD en anglais sur la vie quotidienne du médecin généraliste : enjoy ! (Merci Dr. Martin Winckler !)

Un auteur de polars anglo-saxon : Peter James
Ses "tweets" valent le détour !

Chevaliers des touches : un blog pour écrivants : Martin Winckler, médecin écrivain

Le site internet d'Atul Gawande, chirurgien américain et auteur de trois best-sellers : "Complications", "Better", "The Checklist Manifesto"

A lire, absolument ! :

Le blog d'Aline Feuvrier-Boulanger

Le blog d'Eva Markvoort

"K, histoire de crabes"

"Fameuse famille"

Le site de David Kilgour

A table !

La page web d'une actrice, Julie-Anne Roth

Suggérez vos blogs ou/et sites "coup de coeur" ! A vous de continuer la liste ...