Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


MITx MOOC Course DNA Transcription Launching 10/27

Big Bang Theory

Via Dalya Pallot on Pinterest 10/22/2015

https://www.edx.org/course/molecular-biology-part-2-transcription-mitx-7-28-2x


Week 1 opens Tuesday, October 27, 2015.
    • Lecture 1: Transcription and Assays
    • Lecture 2: Mechanism of Bacterial Transcription
    • Quiz 1 due Tuesday, November 3, 2015 at 14:00 UTC.
Week 2 opens Tuesday, November 3, 2015.
    • Lecture 3: Initiation of Bacterial Transcription
    • Lecture 4: Elongation and Termination of Bacterial Transcription
    • Quiz 2 due Tuesday, November 10, 2015 at 14:00 UTC.
Week 3 opens Tuesday, November 10, 2015.
    • Lecture 5: Eukaryotic Transcription and Nucleosomal Packaging of DNA
    • Lecture 6: Regulation of Transcription Through Histone Modifications
    • Quiz 3 due Tuesday, November 17, 2015 at 14:00 UTC.
Week 4 opens Tuesday, November 17, 2015.
    • Lecture 7: Eukaryotic Transcription - RNA Polymerases and DNA Elements
    • Lecture 8: Eukaryotic Transcription Initiation and Elongation
    • Quiz 4 due Tuesday, November 24, 2015 at 14:00 UTC.
Week 5 opens Tuesday, November 24, 2015.
    • Lecture 9: Eukaryotic Transcription Termination
    • Lecture 10: DNA Binding Regulators of Eukaryotic Transcription
    • Quiz 5 due Tuesday, December 8, 2015 at 14:00 UTC.
Week 6 opens Tuesday, December 8, 2015. 
    • Lecture 11: Mechanism of Transposition
    • Lecture 12: Assays for Transposition
    • Quiz 6 due Tuesday, December 15, 2015 at 14:00 UTC

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