Precision Medicine will need to get out of the pharma silo that is based on symptoms

Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!

Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.

After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC ( to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (

Avatar 2: ethics 2.0

Chinese people and people from New-Zealand do have one thing in common: they are a Nation of farmers. Peasants. Once you've established this, all you can talk about are... differences... There's a gap between both countries: Chinese love the noise and big crowds, they love to rush, they couldn't care less about ecology. Earth health is not an issue for them. They don't give a flying freck...

In New-Zealand, people love to take their time, they also find it highly enjoyable to contemplate a beautiful and quiet landscape... They are all about sustainable farming... Eco freaks... Earth health and sustainable development are top priorities here (throughout the country). "Avatar" is a movie about environment and sustainable production of energy... OK. First things first. "Avatar" is entertainment stuff... The environment storyline musn't be too strident... James Cameron wants to shoot "Avatar 2" (and 3 and 4) with a crew of "as much as possible" Chinese actors. Here, in New-Zealand. Guess why...

My wild guess: because he wants to educate worldwide leading nation (China in just a few years) about earth health...

Ethics is boring stuff, where entertainement is not... Cameron hiring Chinese actors for Avatar 2 etc.? Smart move... and quite the challenge...

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Pic: Chinese New Year in Auckland Feb 22-24 2013.