Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Doomsdare, a medical thriller (action taking place in Beijing) Fall 2016; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2017). Special thanks to Prof. Emmanuel Lincot, lawyer David Kilgour and Isabelle Provost for their help.

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


Welcome!

@cathcoste
People who impress me most:
Jack Andraka, Ray Kurzweil, Eric Topol, Maurice Béjart.

People who changed my life:
Steve Jobs, geneticist and MIT Professor Eric Lander PhD.

My favorite music:
Pomplamoose!

My favorite book (2014):  
J. Craig Venter: "Life at the speed of light".

Favorite writers:
David Mitchell (Cloud Atlas), Philip Pullman ("His Dark Material" -- Movie: "The Golden Compass"), Paul Auster, Jasper Fforde: Fantasy/SF/Comedy/Crime author who lives in Wales, Atul Gawande, Jean Cocteau, Paul Valéry, Arundhati Roy, Amitav Gosh ("The Calcutta Chromosome"), Jhumpa Lahiri ("Interpreter of Maladies"), Novalis, E.T.A. Hoffmann, Tieck, Paul Celan, Christa Wolf ("Cassandra")...

Favorite movies:
Avatar, Cloud Atlas, The Matrix. Life of Pi. 

As I love genomics and musicals, I'm trying to merge both... Monster High Institute of Tech is hitting Growlway: ever heard of the ughsome clawsome MIT Salem genomic musical?





MIT edX Certification in Genomics obtained 18/12/2013. 

Professor: Eric Lander PhD. 

I'm a Personal Genomics Advocate with strong social media skills, interested in genomics entertainment.

Exploring personal genomics involves dedicated microchips. Navigating their own genome on their iPhone, thanks to an "app" that will show a list of variants that can be tailored to the patients' genomic data, and with the help of their physician, patients will be able to become the Risk Manager of their own genome... And oh, yes, of course, we will need to have those FDA guys on board!

To cure diseases like cancer and cystic fibrosis, we will need to target genes (mutations, etc.); not organs.

7.00x The Secret of Life - Intro to Biology

https://www.vizify.com/catherine-coste/connections

Catherine Coste in 3 words: I SELL IDEAS! I LOVE GENOMICS.

Looking for Marketing ideas from London to Singapore!? Look no further!

Passionate about excellence in science (= Perpetual Ascension). Committed to excellence in writing. Scientific + Creative Writing = Marketing.

English, German, French & Basic oral Mandarin Chinese... My family lives in Malaysia (plenty of opportunities for me to improve my Mandarin Chinese), in NY & in Germany -- I'm a German native speaker.

OK, OK, now you're hooked, keep reading.....

A health geek and travel buff, I love meeting new faces. People around me say I'm all about creativity and marketing, new ideas and sustainable everything.

My 2014 favorite book: "Damn Good Advice (for people with talent!)" by George Lois.
I'm a Robin Cook and Tim Burton fan.
Science and society: genomic entertainment.

cath.coste@gmail.com
LinkedIn Page here.
Facebook Wall here.
Twitter Account here.
Google+
Singularity Hub

"A transplant is not a cure": my letter to Steve Jobs.


2013: MOOC student, registered for the course MITx: The Secret of Life, Intro to Biology, by Eric Lander, PhD.  



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3 commentaires:

Low-Coste Innovation Blog a dit…

Aaand yes, I'm employee material:

http://venturebeat.com/2013/08/26/stop-founding-10-signs-youre-employee-material/

Low-Coste Innovation Blog a dit…

"7.00x is an introductory level biology course hosted by professor Eric Lander, who was one of the leaders of the Human Genome Project. Although this course has been designed exclusively for edX, the course content reflects the topics taught in the MIT introductory biology courses and many biology courses across the world. As a student, you will first focus on the structure and function of macromolecules such as DNA, RNA and proteins. You will discover how changes in the structure of some of these macromolecules alters their functions and what the implications of such changes have on human health. As you continue in the course, you will apply an understanding of heredity and information flow within cells to human health and disease and will learn about molecular biological techniques and their potential to impact our changing world. After you complete this course, you will have a foundation in biology that will allow you to understand the remarkable medical revolution going on today.

Students will complete this course in 12 weeks. At the center of each week is a series of lecture sequences that are supported by interactive video tutorials and interspersed exercises or problems. Additionally, students will work on a homework assignment or exam each week. The course will conclude with a comprehensive final exam.

7.00x – The Secret of Life will let you explore the mysteries of biochemistry, genetics, molecular biology, recombinant DNA technology and genomics, and rational medicine."

Ethics, Health and Death 2.0 a dit…

Translating the potential of genomic medicine into routine healthcare is what I am most enthusiastic about. Can you imagine a genetically coded computer, with switches that are in DNA code (A-T-C-G); not in bit code (1-0)? Designing Life, the business and the ethics of synthetic biology, targeting gene mutations to cure cancer; not the organs: I want to be part of it!