Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Doomsdare, a medical thriller (action taking place in Beijing) Fall 2016; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2017). Special thanks to Prof. Emmanuel Lincot, lawyer David Kilgour and Isabelle Provost for their help.

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


"Regenesis: How Synthetic Biology Will Reinvent Nature and Ourselves. A Book Review."

http://clarksearch.com/regenesis-how-synthetic-biology-will-reinvent-nature-and-ourselves
"Regenesis is a book about synthetic biology, which is written on a semi-layman’s level, well just barely. It is an important subject that many of us don’t realize is happening right now and has been for quite some time. Also I like challenges and the book was a challenge to me to see how much I understood. After each chapter I would say, 'ok, one more down. Whew!' Another reason I finally finished the book is that I like to complete things no matter how long it takes to do so. And frankly the subject is important and relevant to my work as an executive recruiter, who often has to search for scientists with genetics and genomic backgrounds. But also I am a glutton for punishment. I just received from Amazon my copy of Craig Venter’s new book 'Life at the Speed of Light' about his adventure into synthetic biology. I thought it would be 'fun' to compare the two books whenever I finished the Venter book. Let’s just hope it doesn’t take 8 months! Truthfully, I would rather be sitting on a tropical beach reading a thriller, but in the interest of science, I will plug along."

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Find the Kindle version on Amazon

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