Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Doomsdare, a medical thriller (action taking place in Beijing) Fall 2016; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2017). Special thanks to Prof. Emmanuel Lincot, lawyer David Kilgour and Isabelle Provost for their help.

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


"No religion will ever be able to stop this"

A picture of me that means a lot to me.
Found it digging in the archives of this blog...

http://ethictransplantation.blogspot.fr/2011/05/quelle-religion-pourra-arreter-le.html
I am in Malaysia, this is May 2011 and I am trying to pray (buddhist style) for the victims of organ trafficking in China. I had to convince the lady in the temple to let me perform this religious ritual as I told her I was acting on behalf of families of dead Chinese prisoners. If you are hungry for the gruesome details, read "Bloody Harvest" by my friend David Kilgour and his colleague, Canadian lawyer David Matas (you'll be sorry you asked). There was really a lot of smoke in there (I can't see it on the picture, but I do recall it) and plenty of monkeys right next to the entrance of this cave (the temple is actually a cave) located in the mountain. "The monkeys are my bodyguards," so I told half jokingly the lady, since my Chinese astrological sign is earth monkey. I was lucky the lady could speak Mandarin Chinese (she didn't speak English), since Cantonese Chinese speakers are very frequent in Malaysia, but Mandarin... not so much. She looked as I performed my "ritual". This is probably the only time in my life I really tried to pray, ironically this was in a religious language I was not at all familiar with: buddhism. When I was done she poured me some tea, like she was Sheldon Cooper in Big Bang Theory, offering Bernadette (Soubirous, that lady of Lourdes Caves in France) a hot beverage. She commented in a sad voice (kind of talking to herself): "No religion will ever be able to stop this".

I really hope that cool CRISPR-Cas 9 genome editing tool will work, sooner than later. Spoke with my friend David Kilgour today. Those atrocities are still going on...

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