Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


The Death Of Brain Death? Working On It - La mort de la mort encéphalique ? On y travaille ...

"HARD knocks to the head are a constant concern in contact sports — and not just in football or boxing, where recent attention has focused. Millions of girls and boys play hockey, soccer, lacrosse and other sports where blows to the head from collisions and falls are part of the game, even in youth leagues and on high school teams. (...)
A crop of new lightweight devices that athletes can wear on the field may help people on sidelines keep better track of hits to players’ heads during games and practice sessions. The devices, packed with sensors and microprocessors, register a blow to a player’s skull and immediately signal the news by blinking brightly, or by sending a wireless alert.
Athletes can wear the devices pressed tightly to their heads, held in place by a headband within a beanie, for example, or even by an adhesive patch and Velcro.
Many of the systems are in research and development, but a few products are coming to the market this summer, including the CheckLight, a washable beanie created jointly by MC10 and Reebok." (Source)

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