Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Doomsdare, a medical thriller (action taking place in Beijing) Fall 2016; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2017). Special thanks to Prof. Emmanuel Lincot, lawyer David Kilgour and Isabelle Provost for their help.

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


"3D Printed Artificial Kidneys Created By UConn Students"


http://www.nuviun.com/blog/3D-Printed-Artificial-Kidneys-Created-By-UConn-Students

"If successful, the project can provide a low-cost but effective alternative to the approximately 2 million people who are on renal replacement therapy worldwide.
In the GCC countries, there is scarce data about ESRD incidence rates, but a 2012 meta-study said that 'Many reports have provided evidence of increasing prevalence of the most common causes of ESRD in the GCC such as obesity, hypertension, and diabetes.'
According to the study, majority of ESRD patients in the GCC countries are on hemodialysis. They would benefit from receiving 3D artificial kidneys if the technology ultimately makes it possible to receive these organs with similar risk compared to receiving real kidneys.
There have been many studies demonstrating how 3D printing technology can go beyond the hype and into applications that impact healthcare, particularly replacing body parts with 3D printed ones, even transplanting live kidneys and livers straight from a 3D printer.
The UConn project recalls to mind a recent, similar project by Japanese surgeons who created 3D-printed tumor-containing kidneys for simulated cancer surgery. Other scientists have also shown how a 3D model of a tumor itself can provide clues to curing cancer.
Other studies demonstrated successful implantation of a 3D printed skull, as well as the creation of 3D-printed artificial eyes, noses and ears." (Source)

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