Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Doomsdare, a medical thriller (action taking place in Beijing) Fall 2016; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2017). Special thanks to Prof. Emmanuel Lincot, lawyer David Kilgour and Isabelle Provost for their help.

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


Jesus CRISPR Super Star





Scientists from Australia & UK have created a “biosensor mouse” that predicts spread of pancreatic cancer cells https://t.co/SxgnGBSh7O
If dying Steve Jobs
And Andrew Lloyd Webber
Wrote a Musicome
"Aren't you tired of all those
revivals?"
It would tell the story
Of that cool genome
editing tool:
CRISPr.
Who is this Jesus CRISPr?
The superstar
Helping parents
With a sick son
Get a Nobel Prize.

"Cracking the Code"
"Fixing the Code"
All done by parents:
The Mission Massimo team.

Nobody else seems
to be in charge.
Not even doctors
Not even scientists
Not even academia
Not even big pharma.

Many thought
Mission Massimo was crazy.
But at M.I.T.
I was told that
"Crazy" could earn you a Nobel Prize
Even if you have no PhD
But end up
Changing medicine.

Jesus CRISPr and Mission Massimo
Did some disease modeling on a mouse
Then they built a platform
To cure thousands of people.

Three decades later
Old Mission Massimo
Steals the show.
Jesus CRISPr Superstar
Sharing a Nobel Prize
With the crazy people.



















 Patients Just Care About A Cure


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