Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Doomsdare, a medical thriller (action taking place in Beijing) Fall 2016; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2017). Special thanks to Prof. Emmanuel Lincot, lawyer David Kilgour and Isabelle Provost for their help.

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


A Risky Business

Seeing ghosts? Some have tried to turn this curse into something useful...


But still, it's a risky business...
Wait. Why not try to turn this curse into... a business?...

No, I don't mean (dead) Bruce Willis helping a (cursed) little boy...


Why not try working with doctors and surgeons? If they are using outdated science, the "cursed" person working with them might see ghosts -- the dead victims of outdated science. Turning the curse/gift into some cool detector of outdated science... Organ transplant medicine could be a great place to start. Scientific polemics around "brain death", organ trafficking worldwide, shortage of organ "donation", surgeons under pressure...

Then the unexpected can happen, like some unfortunate cursed woman meeting with a gorgeous "brain-dead" ghost (not so brain-dead, actually. He was a brilliant mathematician)... Hey, that poor woman may be cursed and miserable and not so good at handling rejection, but at least she gets to choose her Bruce Willis, right?

http://opinionator.blogs.nytimes.com/2016/01/06/my-marriage-didnt-end-when-i-became-a-widow

Now this is something entirely different... The death of a young brain surgeon, his widow trying to find some rest on his grave, as she is in too much pain to be able to sleep... Would you say this woman is seeing a ghost? I don't think so. Seeing a ghost means you've never met this person before (which is aggravating the situation. Yup,there's a reason it's called a curse).

Burton's "Corpse Bride"

Maybe some (dead) victims of outdated science and (dead) young and brilliant scientists will somehow meet and work together on some "mad science" project? I'm curious as to the outcome of this, especially in the context of high-speed internet ghosts and a new emerging religion... Jesus-CRISPR superstar...

I told you. It's a risky business. But isn't the goal of science to remind us that no fate is destined to inevitably befall us (entropy, disease, rejection, unemployment)?

Science is averting fatalities...


Aucun commentaire: