I'm not a client of @OscarHealth currently BUT their ad campaigns make me consider it. Why? Humour. pic.twitter.com/SVJcDcgcS1
— Simon Thompson (@ShowbizSimon) January 28, 2016
Scientific MOOCs follower. Author of Airpocalypse, a techno-medical thriller (Out Summer 2017)
Welcome to the digital era of biology (and to this modest blog I started in early 2005).
To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!
Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.
I am an early adopter of scientific MOOCs. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.
Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).
I love Genomics. Would you rather donate your data, or... your vital organs? Imagine all the people sharing their data...
Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.
Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).
Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).
I love Genomics. Would you rather donate your data, or... your vital organs? Imagine all the people sharing their data...
Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.
Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).
"The Doctor Will See You Now"
Precision Medicine in Organ Transplant
#PrecisionMedicine has incredible potential to protect transplant patients. Catch Dr. Sarwal today at noon. #PMWC16 pic.twitter.com/HUVTRT9sQ1
— UC San Francisco (@UCSF) January 25, 2016
Jesus CRISPR Super Star
Scientists from Australia & UK have created a “biosensor mouse” that predicts spread of pancreatic cancer cells https://t.co/SxgnGBSh7O
— GNN Good News (@GNNGoodNews) January 6, 2016If dying Steve Jobs
And Andrew Lloyd Webber
Wrote a Musicome
"Aren't you tired of all those
revivals?"
It would tell the story
Of that cool genome
editing tool:
CRISPr.
Who is this Jesus CRISPr?
The superstar
Helping parents
With a sick son
Get a Nobel Prize.
"Cracking the Code"
"Fixing the Code"
All done by parents:
The Mission Massimo team.
Nobody else seems
to be in charge.
Not even doctors
Not even scientists
Not even academia
Not even big pharma.
Many thought
Mission Massimo was crazy.
But at M.I.T.
I was told that
"Crazy" could earn you a Nobel Prize
Even if you have no PhD
But end up
Changing medicine.
Jesus CRISPr and Mission Massimo
Did some disease modeling on a mouse
Then they built a platform
To cure thousands of people.
Three decades later
Old Mission Massimo
Steals the show.
Jesus CRISPr Superstar
Sharing a Nobel Prize
With the crazy people.
A big day for genome editing & hope in muscular dystrophy: #CRISPR corrects in mouse model https://t.co/9B8d5kXzbe pic.twitter.com/DaTB0QS7r6
— Eric Topol (@EricTopol) December 31, 2015
Just wrote my review of #CrackingTheCode in German on @Amazon https://t.co/WrJ9OwsXbz cc @missionmassimo @leahkam pic.twitter.com/YyHS6EpUEa
— CATHERINE COSTE (@cathcoste) January 2, 2016
Jesus #CRISPR Superstar, a remake of Lloyd Webber #musical, w/ @MIT stars @eric_lander @zhangf. Superstar: bacteria. https://t.co/03fumRxh77— CATHERINE COSTE (@cathcoste) January 21, 2016
Controversial CRISPR history sets off an online firestorm! More interesting than Amy awards or RealityTV storms... https://t.co/1JdZlxFk5U— Guillaume Plane (@GuillaumePlane) January 20, 2016
Hoping that #CRISPR patent battle will not be a remake of the War of Currents with Thomas Edison VS Nikola Tesla - https://t.co/aWhlx0wufh— CATHERINE COSTE (@cathcoste) January 23, 2016
.@EricTopol Hoping that #CRISPR legal war won't be a remake of the War of Currents with Thomas Edison VS Nikola Tesla #lawyerswillgetricher— CATHERINE COSTE (@cathcoste) January 24, 2016
This biotech company is trying to make a rare disease drug cheaper. Will it work? https://t.co/O3ufrf6bwn pic.twitter.com/ZKAZcAuZVs— STAT (@statnews) 24 Janvier 2016
Interesting CRISPR history https://t.co/HsVJrFd6Ud The seminal observations were rejected in every high-IF journal! pic.twitter.com/cnmT9zXAhT
— Victor de Lorenzo (@vdlorenzo_CNB) January 15, 2016
.@KellyLaMarco @broadinstitute Also a rare form of patient activism #raredisease https://t.co/8dA1D96vrI @leahkam pic.twitter.com/yXEHAXusKo
— CATHERINE COSTE (@cathcoste) January 25, 2016
The videos from this course are useful for a #scifi writer :-) #Programing #EricGrimson #Python #MIT #6001x @cp92isa https://t.co/1ogwoQcMJ0
— CATHERINE COSTE (@cathcoste) January 25, 2016
Intro to Computer Science & #Programming starts today! Learn a new skill in the new year: https://t.co/Lk5X0UIHwA pic.twitter.com/1MaQc40fzb
— MITx on edX (@MITxonedX) January 13, 2016
— CATHERINE COSTE (@cathcoste) January 27, 2016
Creating #biologic #medicines is a complex process comprised of four main steps. https://t.co/RQpLWxE4Rw
— Amgen Biosimilars (@AmgenBiosim) January 19, 2016
Lander's message to Broad Institute regarding "Heroes of Crispr" conflagration. pic.twitter.com/wPe99QhIri
— Antonio Regalado (@antonioregalado) January 29, 2016
Patients Just Care About A Cure
The Very Private Life of My Genome
This is me. Still struggling to find some kind of comfort zone. Any comfort zone would do, I am neither picky nor fussy... But I can't seem to get there, as I keep falling into those bloody holes... Meanwhile, time is ticking...
https://fr.pinterest.com/source/strangeling.com |
Should I start looking for my ancestors and my genetic profile? 23andMe, what do you make of this??... |
http://alecx8.deviantart.com/art/Spock-to-the-Hand-On-Sale-379447391 |
Follow me on Weibo
Just started my #WEIBO account today... Will be micro-blogging about #mhealth #scifi and #airpocalypse in #beijing pic.twitter.com/M1emdBuLW6
— CATHERINE COSTE (@cathcoste) January 25, 2016
CRISPR Side Story
#CRISPR Side Story -- That #NatalieWood feeling... Boston VS California #facts #pressure #lawyerswillgetricher #IP pic.twitter.com/xxeQpSSMd1
— CATHERINE COSTE (@cathcoste) January 25, 2016
"The Patient Will See You Now" French Version
http://tinyurl.com/mawk4vf |
"Patients will have to become data centric." Eric Topol #PWSYN #PM101 #CES2015 #xmed #ehealth http://t.co/rZev7I80vt pic.twitter.com/2Pa4dUrOnl
— CATHERINE COSTE (@cathcoste) January 7, 2015
If I am not mistaken, author of Patient Will See You Now #PWSYN is saying hospitals R becoming obsolete; not doctors http://t.co/rZev7I80vt
— CATHERINE COSTE (@cathcoste) January 7, 2015
Best Book Of The Month Nonfiction (Amazon): "The Patient Will See You Now". Looks like health care needs a massive reboot...
"It's not about looking something up on the internet. It's about your own data, real time." |
Eric Topol MD, Cardiologist: "Patients can now have their own cardiogram on their iPhone." |
Putting patients in charge of their own data, instead of Doctors? |
Putting patients in charge of their data instead of Doctors? Sounds like a printing press revolution. |
"It's not about looking something up on the internet. It's about your own data, real time." EricTopol MD |
Healthcare revolution will comme from outside of healthcare. |
Biology and IT have merged. Time to learn about it
Three beloved artists struck by #cancer this week. Only research can make a difference. Help fight cancer today pic.twitter.com/60Hr6FQBRd— Manolis Kellis (@manoliskellis) January 15, 2016
TY @ReginaHolliday love my jacket. Dying Steve Jobs: "Biology & I.T. have merged" https://t.co/42cI3inq4y #700x #728x pic.twitter.com/gJ0kjzcZBH— CATHERINE COSTE (@cathcoste) July 25, 2015
Airpocalypse Now
Yay, I can access this old crappy blog of mine from Beijing!
Totally loved MIT Tech Review's sci-fi "Twelve Tomorrows"
Trying to write a dystopian fiction about mHealth in China (which explains why I am in Beijing right now...)
#airpocalypse causing 1.4 million of deaths each year in #China! https://t.co/dgQDBZDqkF via @IFLScience @SOLVE_MIT pic.twitter.com/cpcQUwvU6y
— CATHERINE COSTE (@cathcoste) January 19, 2016
http://www.iflscience.com/environment/snow-sponge-toxic-car-exhaust-particles |
At Beijing airport, Jan. 15, 2016 (sorry, not good at taking selfies. Not sure I want to "selfie" myself again...) |
Trying to write a dystopian fiction about mHealth in China (which explains why I am in Beijing right now...)
.@SOLVE_MIT @business In Beijing yesterday. Had to wear a mask even at the airport #airpocalypse #mhealth pic.twitter.com/YEAQSCD0B7— CATHERINE COSTE (@cathcoste) December 22, 2015
RT @business: Beijing's air pollution worsens, although red alert is likely to be lifted https://t.co/egTyN4snce pic.twitter.com/pTvxnnIByx— SOLVE (@SOLVE_MIT) December 22, 2015
"My Health Upgraded" by Berci Mesko MD
Opening of Berci's book: "My Health Upgraded" |
The health app I find most interesting is capturing data on stress & emotions; not a fitness app: @empatica #mHealth https://t.co/C4YVxdlZJ9— CATHERINE COSTE (@cathcoste) January 22, 2016
Reading Berci's book, preparing my review on Amazon... |
checking out the newest generation in #biosensors @empatica #embrace #wearables. @ToxInNewEngland @Dr_Carreiro pic.twitter.com/ihSRJo2Xhc— Peter Chai (@PeterRchai) January 15, 2016
Genomics Festival London
Thank you @nxtstop1 for great curation of #genomicsfest Part 1 https://t.co/U18cRyRbO8 Part 2 https://t.co/9wjoudq4YQ @FLGenomics @FLGLaura
— CATHERINE COSTE (@cathcoste) January 22, 2016
Festival of #Genomics -#GenomicsFest London Jan 19-21, 2016 Curation by @nxtstop1 Part 2 > https://t.co/orXQAs4cvI pic.twitter.com/BO7gEySZc0
— Bernadette Keefe MD (@nxtstop1) January 21, 2016
Festival of #Genomics #GenomicsFest Jan 19-21,2016 London Curation by @nxtstop1 (BKmd)Part 1 https://t.co/Kt0wHPfI3B pic.twitter.com/IuG034s2pt
— Bernadette Keefe MD (@nxtstop1) January 21, 2016
Hey #genomicsfest, slides are now on SlideShare if you had a hard time seeing from the back of the room! @FLGenomics https://t.co/qydx5zI8VQ
— Nils Gehlenborg (@nils_gehlenborg) January 21, 2016
Pictures from #GenomicsFest are now up on our Facebook page: https://t.co/13WFfscoDg
— Illumina Live Events (@illuminaLive) January 21, 2016
My favorite #genomicsfest tweet -- RT @dweinkove: 23 steps from cancer surgeon's knife to sample sequenced on @illumina - Chisholm #PWSYN
— CATHERINE COSTE (@cathcoste) January 22, 2016
"Immaculate suppression"
Immaculate suppression: @nature highlights Lees Lab breakthrough blocking tumor-growth gene https://t.co/Mxt9xxsqsL pic.twitter.com/f6Mi76URI1
— MIT Koch Institute (@kochinstitute) January 19, 2016
.@thomsonreuters has named Professor @eric_lander one of the World's Most Influential Scientific Minds for 2015!
https://t.co/XZLXIRL3Ha
— MITx biology (@MITxBio) January 15, 2016
The IBM and Linux of Genomics
.@missionmassimo is the #Linux of #genomics where @illumina is its @IBM :-) #genomicsfest https://t.co/zDLnNzspuA pic.twitter.com/qlGw9JQ1y8
— CATHERINE COSTE (@cathcoste) January 19, 2016
.@illumina is the @IBM of #genomics #BTOB #IP #Intellectualproperty. Need some envelope pushers w/ #opensource: @missionmassimo #BtoC #PWSYN
— CATHERINE COSTE (@cathcoste) January 3, 2016
If @illumina is the @IBM of #genomics #IP then pple like @missionmassimo could B the @Linux of #genomics #opensource cc @leahkam @geochurch
— CATHERINE COSTE (@cathcoste) January 3, 2016
Reading "GMO Sapiens" by @pknoepfler #CRISPR & #CrackingTheCode by @missionmassimo + @leahkam #genomicsfest @Berci pic.twitter.com/M6XwMgkkfd
— CATHERINE COSTE (@cathcoste) January 20, 2016
Nerd Royalty: Long Live The Telomere!
"we found a way to lengthen human telomeres, turning back the clock by the equivalent of many years of human life"
https://t.co/RbAH38vu8Z
— Erik Brynjolfsson (@erikbryn) January 14, 2016
#genomicsfest @JCVenter would call this "youthanizing people"; Google: "euthanizing death" https://t.co/00615EPVcu pic.twitter.com/MvOhSbhA6s
— CATHERINE COSTE (@cathcoste) January 20, 2016
https://med.stanford.edu/news/all-news/2015/01/telomere-extension-turns-back-aging-clock-in-cultured-cells.html |
Eric Topol MD's 2.0 version is Hero 6's Baymax
"Medical Blockbuster of the Year" (Forbes):
This book already exists as a fiction, by the way... So the 2.0 version of Eric Topol MD would be... Baymax. Healthcare artist and activist Regina Holliday will love this! Baymax Will See You Now.
Actually, Baymax could be quite helpful in "genomic" precision medicine... Who will build him? The IBM of health care or some MIT students, in some kind of open-source mode? Intellectual Property and Digital Rights Management are building tomorrow's empires... San Franciskyoto Side Story...
This book already exists as a fiction, by the way... So the 2.0 version of Eric Topol MD would be... Baymax. Healthcare artist and activist Regina Holliday will love this! Baymax Will See You Now.
"On a scale from 1 to 10..." |
"My hands are equipped with defibrillators...Clear." |
"The entire ecosystem of drug evaluation and regulation is deeply flawed"
She’s gone after pharma giants and governments. Meet @bmj_latest's editor: https://t.co/Nn07qlRIoZ pic.twitter.com/T9VNtdOUp8
— STAT (@statnews) January 9, 2016
A Risky Business
Seeing ghosts? Some have tried to turn this curse into something useful...
But still, it's a risky business...
Wait. Why not try to turn this curse into... a business?...
No, I don't mean (dead) Bruce Willis helping a (cursed) little boy...
Why not try working with doctors and surgeons? If they are using outdated science, the "cursed" person working with them might see ghosts -- the dead victims of outdated science. Turning the curse/gift into some cool detector of outdated science... Organ transplant medicine could be a great place to start. Scientific polemics around "brain death", organ trafficking worldwide, shortage of organ "donation", surgeons under pressure...
Then the unexpected can happen, like some unfortunate cursed woman meeting with a gorgeous "brain-dead" ghost (not so brain-dead, actually. He was a brilliant mathematician)... Hey, that poor woman may be cursed and miserable and not so good at handling rejection, but at least she gets to choose her Bruce Willis, right?
Now this is something entirely different... The death of a young brain surgeon, his widow trying to find some rest on his grave, as she is in too much pain to be able to sleep... Would you say this woman is seeing a ghost? I don't think so. Seeing a ghost means you've never met this person before (which is aggravating the situation. Yup,there's a reason it's called a curse).
Maybe some (dead) victims of outdated science and (dead) young and brilliant scientists will somehow meet and work together on some "mad science" project? I'm curious as to the outcome of this, especially in the context of high-speed internet ghosts and a new emerging religion... Jesus-CRISPR superstar...
I told you. It's a risky business. But isn't the goal of science to remind us that no fate is destined to inevitably befall us (entropy, disease, rejection, unemployment)?
Science is averting fatalities...
But still, it's a risky business...
Wait. Why not try to turn this curse into... a business?...
No, I don't mean (dead) Bruce Willis helping a (cursed) little boy...
Then the unexpected can happen, like some unfortunate cursed woman meeting with a gorgeous "brain-dead" ghost (not so brain-dead, actually. He was a brilliant mathematician)... Hey, that poor woman may be cursed and miserable and not so good at handling rejection, but at least she gets to choose her Bruce Willis, right?
Images of medical history...someday ones from now will look just as crazy https://t.co/5AFLC0XuSL by @erinlschumaker pic.twitter.com/RQ4uKq22CJ
— Eric Topol (@EricTopol) January 8, 2016
http://opinionator.blogs.nytimes.com/2016/01/06/my-marriage-didnt-end-when-i-became-a-widow |
Now this is something entirely different... The death of a young brain surgeon, his widow trying to find some rest on his grave, as she is in too much pain to be able to sleep... Would you say this woman is seeing a ghost? I don't think so. Seeing a ghost means you've never met this person before (which is aggravating the situation. Yup,there's a reason it's called a curse).
Burton's "Corpse Bride" |
Looking for inspiration: go no further than @rocketgirlmd https://t.co/tzOf6MQacM + https://t.co/1AubKh34Hr wow pic.twitter.com/kU3e2wjJEc
— Eric Topol (@EricTopol) January 7, 2016
Maybe some (dead) victims of outdated science and (dead) young and brilliant scientists will somehow meet and work together on some "mad science" project? I'm curious as to the outcome of this, especially in the context of high-speed internet ghosts and a new emerging religion... Jesus-CRISPR superstar...
I told you. It's a risky business. But isn't the goal of science to remind us that no fate is destined to inevitably befall us (entropy, disease, rejection, unemployment)?
Science is averting fatalities...
Human-Animal Chimeras?
Human-Animal Chimeras Are Gestating on U.S. Research Farms
https://t.co/GieyVORcoR
By @AntonioRegalado pic.twitter.com/v9crw1O9fV
— MIT Tech Review (@techreview) January 6, 2016
"By modifying genes, scientists can now easily change the DNA in pig or sheep embryos so that they are genetically incapable of forming a specific tissue. Then, by adding stem cells from a person, they hope the human cells will take over the job of forming the missing organ." (Reddit)
Dr Hiromitsu Nakauchi from @StanfordMed speaking at the @NIH workshop on animals containing human cells #chimera pic.twitter.com/7ZkRt9Uvmz
— Joy Wu (@JoyYWu) November 6, 2015
"The Waiting Room"
My review of @leahkam's #TheWaitingRoom in German on Amazon https://t.co/sV74q5tmqm Hope the book will be available in German/Kindle in Eur.
— CATHERINE COSTE (@cathcoste) January 4, 2016
My review of #THEWAITINGROOM by @leahkam on Amazon https://t.co/u8Ijir5Oae #IsraelNews #MelbourneCity #bookworm pic.twitter.com/zsVwAp1vzR
— CATHERINE COSTE (@cathcoste) January 3, 2016
— CATHERINE COSTE (@cathcoste) January 7, 2016
Girl & gulls |
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