Precision Medicine will need to get out of the pharma silo that is based on symptoms

Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!

Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.

After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC ( to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (

"Do I own my own heart?"

Homo Possessus #Mindmap "Do I own my own heart?"

2 commentaires:

Low-Coste Innovation Blog a dit…

Low-Coste Innovation Blog a dit…

Do we own our own body (and genes and organs)? In Rotterdam in 2007, during the congress "Organ Transplantation: Ethical,
Legal and Psychological Aspects", a French surgeon, Henri Kreis, MD, presented a text regarding "conditional societal appropriation of body parts": "Whose Organs are they, anyway?"

"Societal conditional appropriation of body parts could well be the best answer to society needs along with the respect of individual autonomy. Society becoming the owner of the corpse, but respecting the autonomy of the person, might be the real answer to all major questions raised today: organ procurement, organ allocation, organ trade, consent, and family involvement. (...) [I]n order to acknowledge the principle of autonomy, a society willing to use the concept of appropriation to favor organ procurement, should accept individual, but not family, refusal to donate, making this appropriation conditional to individual refusal. Decision will derive from a societal imbalance between individual and collective liberty. It is a true societal choice. Currently, in view of other public responses, there is little reason to believe that this concept would be easy to introduce politically, prior to society becoming fully informed and accepting its benefits. The ‘goodwill’ pathway, however, appears to have reached a dead end. Replacement medicine may not survive if we continue to repeat the same mistakes over and over again. Let us keep asking our societies these difficult questions, and hopefully this will generate appropriate responses, even if the process takes some time." Read the whole text here: