Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


Fair Trade Electronics Offering Low-Tech And Low-Cost Solutions

Green and biodegradable electronics - DIY Bio-Based Electronics

"We live in a world where the lifetime of electronics is becoming shorter, now approaching an average of several months. This poses a growing ecological problem. This brief review will present some of the initial steps taken to address the issue of electronic waste with biodegradable organic electronic materials. Many organic materials have been shown to be biodegradable, safe, and nontoxic, including compounds of natural origin. Additionally, the unique features of such organic materials suggest they will be useful in biofunctional electronics; demonstrating functions that would be inaccessible for traditional inorganic compounds. Such materials may lead to fully biodegradable and even biocompatible/biometabolizable electronics for many low-cost applications. This review highlights recent progress in these classes of material, covering substrates and insulators, semiconductors, and finally conductors."

"Pourquoi ne pas rêver d’une électronique biodégradable, assemblée par des microbes à partir de matières biologiques abondantes sur toute la surface de la planète ?
Ce rêve est plus réel qu’il n’y paraît. Mihai Irimia-Vladu, professeur à l’université de Linz, rapporte dans une publication de 2006 la construction d’un transistor à base de cafféine, de béta-carotène et de sucre caramélisé. Si les processus mis en oeuvre par ce professeur pour produire ses transistors sont loin d’être suffisamment low-tech pour être DIY, la base de matériaux, bio-sourcés et bio-dégradables, n’en est pas moins radicalement prometteuse."

Green and biodegradable electronics:
https://www.jku.at/JKU_Site/JKU/ipc/content/e166717/e166907/e174991/e178578/2012-021.pdf

DIY Bio-Based Electronics
http://www.lapaillasse.org/news/1120/diy-bio-based-electronics (French version)

Do-it-yourself biology: challenges and promises for an open science and technology movement
http://www.lapaillasse.org/wp-content/uploads/2013/08/Landrain_DIYbio_SSBJ_2013.pdf

2 commentaires:

Low-Coste Innovation Blog a dit…

Genetically engineered plants to produce an organic polymer that can be used to make biodegradable plastic http://www.gizmag.com/metabolix-bioplastic-switchgrass/28578/#!

Low-Coste Innovation Blog a dit…

Fair-Trade Smartphones For The Geek With A Conscience. End 2013: the fair-trade smartphone will be available (mail-order).

http://www.worldcrunch.com/business-finance/fair-trade-smartphones-for-the-geek-with-a-conscience/fairphone-van-abel-mobile-cell-android/c2s11063/