Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Doomsdare, a medical thriller (action taking place in Beijing) Fall 2016; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2017). Special thanks to Prof. Emmanuel Lincot, lawyer David Kilgour and Isabelle Provost for their help.

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


Free’s Xavier Niel To Launch 1000startups In Paris, The World’s Biggest Incubator

Romain Dillet

03 - Vue du silo compactus
"While the name is very reminiscent of 500 Startups, 1000startups is a brand new crazy project from Free CEO Xavier Niel. With the help of the Caisse des Dépôts, Niel wants to create the world’s biggest incubator in the heart of Paris. As the name suggests, its 320,000 square feet should be enough to help 1,000 startups.
Located in the 13th arrondissement at the halle Freyssinet, 1000startups will open in 2016. The team had to buy the building from the City of Paris for $94 million (€70 million) and will invest $108 million (€80 million) over the next few years. Niel is clearly the major investor as the Caisse des Dépôts will only contribute 5 to 10 percent of the budget.
Many investing institutions, such as the public VC firm Bpifrance, will relocate to 1000startups. During the project’s unveiling, the team presented its vision of the perfect incubator, with multiple locations to share ideas and meet new people.
Yet, 1000startups looks flawed. While Niel calls it an incubator, it seems to be closer to a coworking space. For example, Free’s CEO didn’t say whether he plans to invest in the companies that will work in this new location. No word on how it plans to select startup teams either.
Moreover, it is once again a partly public initiative that doesn’t want to generate any profit. That’s not how you find the best startups, cherish them, and make them succeed. Other initiatives such as Paris-based TheFamily looks more appealing.
1000startups should therefore be treated as a good project to rent cheap startup offices in Paris. It could create a new startup network for French startups. But startups shouldn’t expect advice and introductions from the team behind 1000 startups."

http://techcrunch.com/2013/09/25/free-xavier-niel-to-launch-1000startups-in-paris-the-worlds-biggest-incubator/

"But startups shouldn’t expect advice and introductions from the team behind 1000 startups." Mabye that's too soon to tell...

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