Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Doomsdare, a medical thriller (action taking place in Beijing) Fall 2016; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2017). Special thanks to Prof. Emmanuel Lincot, lawyer David Kilgour and Isabelle Provost for their help.

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


"Thinking in New Boxes: A New Paradigm for Business Creativity": Luc de Brabandère (Boston Consulting Group)




"This innovative book challenges everything you thought you knew about business creativity by breaking creativity down into five steps:

Doubt everything. Challenge your current perspectives.
• Probe the possible. Explore options around you.
• Diverge. Generate many new and exciting ideas, even if they seem absurd.
• Converge. Evaluate and select the ideas that will drive breakthrough results.
Reevaluate. Relentlessly. No idea is a good idea forever. And did we mention Reevaluate? Relentlessly."

"Thinking in New Boxes is a five-step guide that leverages the authors’ deep understanding of human nature to enable readers to overcome their limitations and both imagine and create their own futures. This book is a must-read for people living and working in today’s competitive environment." —Ray O. Johnson, Ph.D., chief technology officer, Lockheed Martin.

Luc de Brabandere is a fellow and a senior advisor in the Paris office of the Boston Consulting Group. He leads strategic seminars with boards, senior executives, and management from a wide range of companies looking to develop new visions, new products and services, and long-term scenarios to prepare for the future. He is the author or co-author of nine books, including The Forgotten Half of Change: Achieving Greater Creativity through Changes in Perception, and a regular columnist for various newspapers in France and Belgium. Prior to joining BCG, he was the general manager of the Brussels Stock Exchange.

Alan Iny is the global topic expert for creativity and scenario planning at the Boston Consulting Group, based in the New York office. He has trained hundreds of executives and BCG consultants, and facilitated a wide range of workshops across industries, on topics related to bringing creative approaches to business. Iny received his MBA from Columbia Business School and holds an honors BSc in mathematics and management from McGill University.

Source: Amazon.

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