Precision Medicine will need to get out of the pharma silo that is based on symptoms
Welcome to the digital era of biology (and to this modest blog I started in early 2005).
To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!
Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.
After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.
Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).
I love Genomics. Would you rather donate your data, or... your vital organs?
Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.
Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).
"Heart attack damage repaired using gene therapy"
"Heart attacks cause cells in the affected area to stop beating and become encased in scar tissue, but researchers believe the damage may not be permanent.
Using a combination of genes they were able to coax the scar-forming cells into a state which closely resembles healthy, beating heart cells, suggesting the condition is reversible.
The scientists, from the Gladstone Institutes in America, had already demonstrated their technique on mice but have taken a step further by doing the same to human heart cells in a laboratory.
The study is a 'proof of concept' that the scar-forming cells, known as fibroblasts, 'can be reprogrammed successfully into beating heart cells,' and mend the heart from within, they said.
Dr Deepak Srivastava, who led the study, explained: 'Fibroblasts make up about 50 per cent of all cells in the heart and therefore make up a vast pool of cells that could one day be harnessed and reprogrammed to create new muscle.'" (http://www.telegraph.co.uk/health/healthnews/10260701/Heart-attack-damage-repaired-using-gene-therapy.html)