Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Doomsdare, a medical thriller (action taking place in Beijing) Fall 2016; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2017). Special thanks to Prof. Emmanuel Lincot, lawyer David Kilgour and Isabelle Provost for their help.

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


"About A Boy: 3D Printed Heart Model Saves Young Life"

http://www.forbes.com/sites/tjmccue/2014/02/26/about-a-boy-3d-printed-heart-model-saves-young-life
"'If a picture is worth 1,000 words, then a model is worth 1,000 pictures,' said Gornet, whose center had already done models of spinal defects and tumors.
Using data from thousands of cross-sections of hospital X-rays, Gornet chose a flexible polymer known as ‘Ninja Flex’ to create a 3-D model. In about 20 hours on a $2,500 printer, he created a replica of the heart at a cost of about $600.
The world of bioprinting is rapidly changing how we think about healthcare and healing. In this young boy’s case, his heart was modeled with 3D software, and that helped surgeons see the problems and create solutions before the critical moments of surgery. Stanford researchers have been reporting progress on modeling the heart and other organs.
Scientists and doctors are teaming up all around the world to print organs, layer by layer, with 3D printing technologies. From 3d printed livers at San Diego-based bio-printing company Organovo to 3d printing skin cells at Wake Forest University, all from your own cells.
The story of this 14 month-old baby is inspiring and amazing, if you pause to think about it. By thinking about other options, surgeon Erle Austin found a way, via a savvy engineering team with a MakerBot 3d printer, to save the child before he started the critical surgery.

Correction: I originally put Erie for Dr. Austin’s first name. His full name is Erle H. Austin III." (Source)

Aucun commentaire: