Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


IBM Watson coming to London!

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http://www.kurzweilai.net/smart-machines-ibms-watson-and-the-era-of-cognitive-computing
Catherine Coste, author of this blog. I come from France, native german speaker. Previously, I earned a certificate in a genomic course, "7.00x the secret of life" MITx (edX). I love languages, genomics. Post-graduate in German litterature and language (La Sorbonne, Paris). Fascinated in IBM Watson. Currently a MOOC student: "Logic: Language and Information 1", University of Melbourne, Coursera -- study of Watson analytics included in this MOOC!


Translating the potential of genomic medicine into routine healthcare is what I am most enthusiastic about. Working on a genetically coded computer, with switches that are in DNA code (A-T-C-G); not in bit code (1-0), designing life, the business and the ethics of synthetic biology, targeting gene mutations to cure cancer; not the organs: I want to be part of it! Interoperability is what Watson is about.

Interoperability? Does this mean that Google Glass and Watson (as an app for iPhone & Google phone) and iBlue Button (with Microsoft Health Vault) and Human Longevity Inc.
and AliveCor Heart Monitor and Scanadu (a handheld medical "tricorder") and the cloud will interact?! I am not a techy person, however I am at my best when working with them.

Since the digital age of biology is a revolution that is happening right now under our feet, we all need to anticipate the $100 genome era and the P4™ medicine revolution -- P4 Medicine (Predictive, Personalized, Preventive, & Participatory), which is catalyzing a Revolution from Reactive to Proactive Medicine.  




Valérie Cabaret-Bourgoin, French paintress. "Not So Blind", 100x80 cm, 2014.

An expat wannabe, I realize that nothing much is going on in France (my country), where it is forbidden by law to have your genome sequenced.

Genomics and Watson is the equation at hand. Eric Lander PhD says we will need one or two decades before we can turn cancer into some kind of chronic disease... Hope Watson helps us speed up the process a little bit...

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