Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


Beijing Airpocalypse Now

At Beijing Airport, 21 Dec. 2015
Red alert politics (as issued by the Chinese Government): No-More-Red-Alert-Warning. Really? I am in the middle of a pollution peak, this is 5:00 am local time and even at the aiport, I have to wear a mask. Only a few people do, and on the train and in the city I notice that masks worn by most people are a joke.

Even at the Science Museum in Beijing I was wearing this mask. Beijing looks like this is a country at war. What will happen if you don't wear a mask? You'll get runny nose and eyes, even indoors. Happens to me all the time. Would be fun to tell the Chinese police I am an app developer, trying to foresee when the population is going to die due to high levels of pollution, which would be a very interesting information to have for the governement... They could then "divulge" this information to protect the country's productivity. Send unproductive people (retired people for ex.) to highly polluted places, and prevent highly productive people from getting harmed by pollution. Make it happen, thanks to some mHealth app... Productive people could wear an electronic bracelet (like the one prisoners have to wear) and if they happen to be in a polluted zone where they are not supposed to be, they could be stopped by the police.

Information belongs to Chinese officials. An app that does not give real time information but only tells you what the Chinese government wants you to do... My health is government-owned, my destiny is linked to my productivity. Made-in-China mHealth. Dystopian satire? Hardly.

Looks like it could happen... Beijing is the place to be if you are a scifi writer...

"The Patient Will See You Now" Chinese version (actually the book was translated in Chinese), adapted into films? Great potential...

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