Precision Medicine will need to get out of the pharma silo that is based on symptoms

Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!

Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.

After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC ( to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (

The Doctor-&-Patient "Nerdvana Annihilation" Topology

My favorite musical is "New West Side Story", which is an adaptation of "The Creative Destruction of Medicine" by cardiologist Eric Topol MD, but there's kind of a fly in the ointment...
Ever seen that old musical in New New York, Matilda?
Lyrics from "Naughty" -- Matilda The Musical
Stupidity, gory?? Paternalistic medicine??!! Yuck.

This nerdvana thing drives me crazy...

So Sheldon Cooper gave me a hot beverage to comfort me...
He also told me IBM's Watson might help...
Watson?!? WTF???!!! 

Oh, I see... So they did change their story after all... "The Rockstar Patient Will See You Now"

"A.I. + Rockstar; Doctor + Amy Wong.
What could possibly go wrong?"
"I'm a Doctor. I thrive in a competitive environment.  I got selected for med school through competition. I've studied anatomy and organs for 15 years but I spend most of my time hating my colleagues."

"Doctor-&-Patient 'Nerdvana Annihilation'? Paternalistic medicine can kiss your shiny metal ass, Bender!"

Aucun commentaire: