Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


My Kinky MOOCs


My Kinky MOOCs: read about the begining of the MOOC adventure here.
http://kinkybootsthemusical.com/about.php
http://www.frontlinegenomics.com/wp-content/uploads/3090_FG_Magazine_Aug_FULL_DOC.pdf (p 44-45)

Student profile: a far cry from ideal.
Yes, That's me. Self confidence level: low. I'm a creative person, which means my mood fluctuates a lot. I'm not a great scientist (plagued by data blindness, logic is not my cup of tea), me learning computer coding is comedy material, but I love writing, especially fiction that takes place in the future: exploring human emotions in the context of new technologies. I really want to understand genomics and the future of medicine. Dreaming about girly science and trying to make it happen.

https://www.facebook.com/MITxBio
A MOOC is a massive open online course, at least this is what it's supposed to be. But they call me an early adopter for a reason, right? Early adopter stands for adept of a technology that is not implemented yet. There will be bugs like if you make one little mistake in a complex question, your answer for the whole problem will be graded as zero instead of, say, 12/15. By the time they fix the bugs, the MOOC course can be over, so you'd better be good at finding answers where there is no bug (if you want a decent grade, you are left with a margin of error of less than 2%). I chose MIT because their pedagogy is outstanding and they have the best "deep dive" videos in the world, which boils down to the fact that understanding complicated stuff becomes entertaining. It's a weird combination of magic (the great pedagogy) and messy (the bugs, molecules, proteins and assays, both in biology and IT. Remember, biology is going digital). In my humble opinion, the advantages outweigh disadvantages such as compacting two month's worth of work in one week: Python coding in genomics and Eric Lander lectures in ONE week, seriously? I call this "Life at the Speed of Light". (Quantitative Biology Workshop, week 5). 

"I'm on my way from misery to happiness today"

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