Precision Medicine will need to get out of the pharma silo that is based on symptoms

Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!

Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.

After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC ( to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (

"We think heroism is trainable, we’re trying to make people aware that most heroes are ordinary people."
"(...) Zimbardo spent years studying how certain situations can give rise to evil. He appeared as an expert witness in an Abu Ghraib guard’s trial and wrote an acclaimed book called The Lucifer Effect. As he finished his book manuscript, though, he realized the strain of focusing on the worst in human nature was getting to him. He thought about Christina Maslach, the psychologist who would eventually become his wife, and how she had interceded during the Stanford Prison Experiment, telling him what he was doing to his subjects was terrible. He knew it had taken courage for Maslach to speak up, and he pondered why some people step forward to help others even at personal risk, while most are content to remain on the sidelines. Inspired, he decided to devote himself to studying and promoting heroism, and he founded his own nonprofit, the San Francisco-based Heroic Imagination Project (HIP). 'We think heroism is trainable,' he says. 'We’re trying to make people aware that most heroes are ordinary people.'

At first glance, Zimbardo’s career shift might seem like a dramatic turnabout, but it’s actually a very logical follow-on to his earlier work."

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