Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Doomsdare, a medical thriller (action taking place in Beijing) Fall 2016; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2017). Special thanks to Prof. Emmanuel Lincot, lawyer David Kilgour and Isabelle Provost for their help.

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


23andMe, the FDA and The Big Bang Theory


"23andMe: Here's how I got diagnosed with some terminal illness but was able to debug this diagnosis and got my health back"

23andMe case: should medical information (data) be kept by specialists or is it up to the patient to learn how to decode his own data/information? MOOCs in genomics will give the tools to patients if they want to do their own (genomic) risk management, instead of trusting blindly -- which can be the biggest risk of all...
Interesting

http://mntmn.com/pages/23andme.html

Remember it took 24 years to the FDA to approve HIV tests outside of hospital. How many avoidable and unnecessary HIV infections during those 24 years?

http://features.blogs.fortune.cnn.com/2012/07/09/oraquick-hiv-test/

Intéressant cas avec 23andMe : Faut-il réserver l'information médicale aux spécialistes ou le patient doit-il apprendre à la décoder lui même ?
Traduction en anglais : http://mntmn.com/pages/23andme.html

Une autre histoire à mettre en balance : la FDA a mis 24 ans pour approuver les tests HIV en dehors du circuit hospitalier ; combien de contaminations supplémentaires cela a causé ?

http://features.blogs.fortune.cnn.com/2012/07/09/oraquick-hiv-test/

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