Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Doomsdare, a medical thriller (action taking place in Beijing) Fall 2016; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2017). Special thanks to Prof. Emmanuel Lincot, lawyer David Kilgour and Isabelle Provost for their help.

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


Here's how some German teacher in France earns herself a MIT certificate in Genomics. Thank you Eric Lander PhD!



https://www.edx.org/course/mitx/mitx-7-00x-introduction-biology-secret-1014
Thank you for this amazing course! I am so proud I could be part of the journey and... earn myself a MIT certificate!! When starting this course back in early September 2013, I had no idea what genomics really was. I only knew one thing for sure: it's the revolution of the century, it's damn important -- so told me dying Steve Jobs and I was terribly impressed as you might imagine -- and I made some kind of life changing decision: I wanna learn... 

Our healthcare system is PATENT centered. How about we try to make it a little bit more PATIENT centered? 

BIG thanks to the MOOC "7.00x" team because this is exactly what you guys do: enabling people who want to learn (but are no scientists, just, say, plain people) to... learn. I will never forget this... I owe you one... 

Now what? I want a job that gets me involved in the science of the human genome. This revolution is happening right under our feet.

==> Take a look at my LinkedIn page here...

In France, citizens are not allowed to get their DNA sequenced if they want to. It is forbidden by law... Wanna talk about the immorality of blocking humans from their own genome?...

Introduction to Biology - The Secret of Life


"Explore the secret of life through the basics of biochemistry, genetics, molecular biology, recombinant DNA, genomics and rational medicine."

 About this Course


"7.00x is an introductory level biology course hosted by professor Eric Lander, who was one of the leaders of the Human Genome Project. The course content reflects the topics taught in the MIT introductory biology courses and many biology courses across the world. As a student, you will first focus on the structure and function of macromolecules such as DNA, RNA and proteins. You will discover how changes in the structure of some of these macromolecules alters their functions and what the implications of such changes have on human health. As you continue in the course, you will apply an understanding of heredity and information flow within cells to human health and disease and will learn about molecular biological techniques and their potential to impact our changing world. After you complete this course, you will have a foundation in biology that will allow you to understand the remarkable medical revolution going on today.
Students will complete this course in 14 weeks. Each week features a series of lecture sequences that are supported by interactive video tutorials and interspersed exercises or problems. Students will work on a homework assignment or exam each week. The course will conclude with a comprehensive final exam. Additionally, for teachers of science, we have forged a collaboration with the National Science Teachers Association (NSTA) to facilitate understanding of challenging content and help with practical classroom applications of the courseware. Visit NSTA/MITx for details. 7.00x – The Secret of Life will let you explore the mysteries of biochemistry, genetics, molecular biology, recombinant DNA technology and genomics, and rational medicine. We are excited to take this journey with you!"


https://www.edx.org/course/mitx/mitx-7-00x-introduction-biology-secret-1014 

7.00x Course Staff

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