Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Doomsdare, a medical thriller (action taking place in Beijing) Fall 2016; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2017). Special thanks to Prof. Emmanuel Lincot, lawyer David Kilgour and Isabelle Provost for their help.

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


Software Tools that are being used for MIT Genomics courses

The course-specific software tools are GeneX, IGV, Molecule Editor.

However, you become well acquainted with all of those:

Molecule Editor
jsmol (protein viewer)
IGV (gene and genome viewer)
GeneX (edit a gene)
Designing Proteins in 2-D
jsVGL (virtual genetics lab)

Here are a few print screens. Try to guess which is which... I'm not allowed to show more (hopefully I don't get in trouble for posting this...)

Editing molecules:

Molecule Editor

jsVGL

IGV-Lite, my favorite

Folding and editing proteins
IGV Gene Viewer
JSmol

Surprise!!

MIT Gangnam Style (MIT 강남스타일)

1 commentaire:

Low-Coste Innovation Blog a dit…

Chromosomal walking in Gangnam style! ;-)