"The mosaicism of our #brain DNA is far greater than anticipated"
The mosaicism of our #brain DNA is far greater than anticipated http://t.co/0NcjQhJsWZ @sciencemagazine @salkinstitute #genomics
— Eric Topol (@EricTopol) October 31, 2013
"Our Final Invention" by James Barrat
CK out new Book: Our Final Invention,author James Barrat. #ArtificialIntelligence and the end of the human era.Concerned? If not you should
— Courtney Benson (@webeneer) October 6, 2013
Our Final Invention. My copy has arrived. @jrbarrat pic.twitter.com/bYBfJ6V547
— Shilo Haapala (@shilohaapala) October 19, 2013
OUR FINAL INVENTION an "excellent read for technophiles and readers wishing to get a glimpse of the near future" http://t.co/KAmmr0uq5d
— William Clark (@wmclarkassoc) October 18, 2013
The Real Privacy Problem
The Real Privacy Problem http://t.co/YzZf9JMurj
— Portable Genomics (@portablegenomic) October 31, 2013
Pharma Showing Interest in Open Systems for Drug Discovery
Pharma Showing Interest in Open Systems for Drug Discovery | Xconomy http://t.co/8MBv2kj8i1 via @xconomy @wilbanks
— Portable Genomics (@portablegenomic) October 31, 2013
A medical matryoshka doll...new potential approach to triple neg breast cancer
A medical matryoshka doll...new potential approach to triple neg breast cancer http://t.co/olJIYGV9sD @TheEconomist @acsnano
— Eric Topol (@EricTopol) October 31, 2013
"Wrangling data from a huge variety of gadgets"
Wrangling data from a huge variety of gadgets http://t.co/sJ2Mj1tcsp "how do you manage the reams of data?" on fitness, but applies =-> med
— Eric Topol (@EricTopol) October 31, 2013
"Digital Health and the Frankenstein Syndrome" (Halloween post)
Halloween post--Technology, Digital Health and the Frankenstein Syndrome http://t.co/JPYuAEjiO9 via @forbes #digitalhealth @medtronic
— JOHN NOSTA (@JohnNosta) October 31, 2013
MIT Wristband Could Make Air Conditioning Obsolete
"Here’s a scary statistic: In 2007, 87 percent of households in the U.S. used air conditioning, compared to just 11 percent of households in Brazil and a mere 2 percent in India. Another one: By 2025, booming nations like those are projected to account for a billion new consumers worldwide, with a corresponding explosion in demand for air conditioning expected to arrive along with them. Keeping indoor spaces at comfortable temperatures requires a huge amount of electricity–especially in sweltering climates like India and Brazil–and in the U.S. alone it accounts for a full 16.5 percent of energy use."
MIT Wristband Could Make AC Obsolete | Wired Design | http://t.co/8IcIIwZr9r http://t.co/spG6eXi9Ym
— CATHERINE COSTE (@cathcoste) October 31, 2013
New Google Glass is on the way
New Google Glass is on the way http://t.co/N2HEaWp2mD
— Portable Genomics (@portablegenomic) October 30, 2013
A #biotech that could save millions of lives, cheaply & efficiently, all over the world
"A sweeping new synthetic vaccine platform that poses infinite possibilities for researchers and could produce novel preventive and therapeutic drugs is a quintessential example. In this interview with The Life Sciences Report, Cox delivers a single name that holds the potential to save lives on a mass scale, cheaply and efficiently, in both the developed and developing world—and deliver health and wealth to investors' portfolios as well."
Patrick Cox discusses a #biotech that could save millions of lives, cheaply & efficiently, all over the world: http://t.co/wnaNZoJDF8
— Life Sciences Report (@SWLifeSciences) October 24, 2013
Coming soon"The Creative Destruction of Lab Medicine" #CDoM
New intvw, coming soon"The Creative Destruction of Lab Medicine" RT @Medscape w/ Elizabeth Holmes, 29yo CEO Theranos pic.twitter.com/6uhWdNRXFX
— Eric Topol (@EricTopol) October 30, 2013
Disney villains get the “Chicago” treatment
RT @YouTube: Disney villains get the “Chicago” treatment from Todrick Hall, Adam Lambert and friends. http://t.co/SPZ9vQYyM8
— Digital LA (@DigitalLA) October 30, 2013
OpGen and Hitachi High-Technologies to Develop Human Chromosome Mapping Service
OpGen and Hitachi High-Technologies to Develop Human Chromosome Mapping Service - Yahoo Finance http://t.co/9xkKbrdEDj Saw them at #ASHG2013
— Dale Yuzuki (@DaleYuzuki) October 30, 2013
Interested in Genetics and Molecular Biology? Think MOOC - the best one
Couldn't agree more... Lots of work, though, and not only Sunday morning...
I love to start my Sundays with lectures from @eric_lander via edx MOOC, he explains macromolecule biology so clearly.
— Beth Hart (@poots) October 27, 2013
Ensuring Latin America is full partner in genomic medicine revolution
Deeply moved by @CarlosSlim's visionary $74m gift to @BroadInstitute to ensure Latin America is full partner in genomic medicine revolution
— Eric Lander (@eric_lander) October 29, 2013
Genomic Musical Hitting Broadway!
 |
| https://www.facebook.com/possessus |
Well, don't be so sure... Oh, and by the way...
Do we own our own body (and genes and organs?)
Medicine and science are enhancing and transforming mankind (homo sapiens). We read about this in the paper everyday, worldwide. It's happening now, right under our feet...
The musical about the Human Genome Project I'm working on is about people and who owns them, about cyberpunks, bio hackers, DIY Bio, biotechs and "pig" pharma. Digital devices, sensors, big and small data, genomics, 3D printing, bioengineering, organ replacement technologies (and donation and trafficking): what do WE THE PEOPLE have to say (and sing) about this?
Possessus, from the Latin word meaning both possessing and possessed.
This Facebook page "Homo Possessus" is aimed at knowledge sharing for all and by all, so your contribution is welcome and wanted!
Screwed up scientists, really? A Crick and Watson behind-the-scene story
#genomics #CDoM Screwed up scientists, really? A Crick and Watson behind-the-scene story http://t.co/o0I0bc9RpM
— CATHERINE COSTE (@cathcoste) October 30, 2013
 |
| The sugar-phosphate backbone is on the outside and the four different bases are on the inside of the DNA molecule. |
Actually those two guys, Crick and Watson, were outsiders, regarded by their academic collegues as total idlers. They were thought of as unreliable kids, screwed up scientists, good enough for talking at any great length and making ridiculous models and achieving nothing but this one thing in particular: annoying and annoying further serious scientists working hard on their serious experiments... Academic insiders are the real thing, you see... Not those idle kids who will take nothing seriously... Except that Crick and Watson got famous for their achievements in genomics... They've discovered the molecular structure of DNA (the double helix), which got them a Nobel Prize.
 |
| http://petapixel.com/2013/10/29/honored-photograph/ |
This photograph has been taken by 9 "screwed up pilots" whose story reminds me of Crick and Watson's... A misfit crew, made of nine perfect army rebuttal examples, each in its own style, and their DIY plane went on the deadliest mission ever (without proper authorization, by the way, just like Crick and Watson working on the double helix of human DNA), in South Pacific in the early days of World War II...
The Most Honored Photograph
Ohio State Marching Band Stuns With Movie-Themed Choreography
Superman, Lord of the Rings, Harry Potter, Jurassic Park
Superman at 2:04 my favorite (fanfare is
just not my thing, though)...
Superman at 2:04 my favorite (fanfare is
just not my thing, though)...
"La langue française est morte ce matin : le Larousse explique que digital est un synonyme de numérique"
"La langue française est morte ce matin : le Larousse explique que digital est un synonyme de numérique"
Pour Larousse, Digital est bien «synonyme» de Numérique
The Guide to the Future of Medicine white paper by @berci is coming out this week
Exciting! The Guide to the Future of Medicine white paper by @berci is coming out this week #s4pm pic.twitter.com/KACQqH23tN
— Scanadu (@scanadu) October 29, 2013
Scientists Can Now Genetically Modify Facial Features
The future of aesthetic surgery: genomics?
Scientists Can Now Genetically Modify Facial Features http://t.co/cW8C1bqZZk
— Jean Michel Billaut (@Billaut) October 29, 2013
"Neuroscientists discover new 'mini-neural computer' in the brain"
Neuroscientists discover new 'mini-neural computer' in the brain http://t.co/BayeEdVX20
— Jean Michel Billaut (@Billaut) October 28, 2013
World's first GM babies born
World's first GM babies born http://t.co/UGQ2J2M1XC
— lara kamhi (@larakami) October 28, 2013
Cardiologist says: "The remedies are in our own back pockets"
Couldn't help but see t/ connection reading Siddhartha Mukherjee's Emperor of all Maladies today @EricTopol #mHealth pic.twitter.com/RKqnWAsF0r
— Evan David Muse (@EvanMuse) September 23, 2013
 | ||
|
Qiagen Acquires CLC bio
Qiagen Acquires CLC bio! via @allseq http://t.co/DdTxGoFvwL
— Portable Genomics (@portablegenomic) October 25, 2013
'Born-to-die' technology
Biosensors that do their thing, then disappear http://t.co/JKBlQFtONY @guardian
— Eric Topol (@EricTopol) October 27, 2013
Billautshow: "Professionnels de santé proposez donc des services en ligne à vos patients !"
Connaissez-vous Richard Good from Lyon ? tuOtempO : professionnels de santé proposez donc des services en lign... http://t.co/z6M2lLtG3X
— Jean Michel Billaut (@Billaut) October 27, 2013
 |
| http://billaut.typepad.com/jm/2013/10/connaissez-vous-richard-good-from-lyon-tuotempo-professionnels-de-sant%C3%A9-proposez-donc-des-services-e.html |
http://billaut.typepad.com/jm/2013/10/connaissez-vous-richard-good-from-lyon-tuotempo-professionnels-de-sant%C3%A9-proposez-donc-des-services-e.html
"Pourquoi doit-on communiquer avec les personnes en état végétatif ?"
 |
| http://moviehypesa.blogspot.fr/2012/01/beetlejuice-2-in-development.html |
http://www.evolute.fr/relation-aide/communiquer-etat-vegetatif
Plein d'idées pour Tim Burton et son (très attendu) Beetlejuice II... ;-)
Is This Robotic Surgeon Broken Beyond Repair? (ISRG)
Is This Robotic Surgeon Broken Beyond Repair? (ISRG): http://t.co/kzcsU4tSgc via @themotleyfool
— Leo Sun (@leokornsun) October 18, 2013
A kidney for $10,000? Paying donors actually pays off, new study finds
A kidney for $10,000? Paying donors actually pays off, new study finds http://t.co/wQlzwtzC4K
— NBC News Health (@NBCNewsHealth) October 25, 2013
Opinion: Why selling kidneys still won't work http://t.co/3CBhu13lCW
— NBC News Health (@NBCNewsHealth) October 25, 2013
Achieving ultimate geekdom
If you're paying for stuff with Bitcoin using Google Glass then you have achieved ultimate geekdom: http://t.co/eWEfcyBnR1
— josiah hobson (@josiah17) October 19, 2013
The Genetic Code: a pretty looking look up table
 |
| Straight Out of the Resource Boxes of MOOC MIT 7.00x "The Secret of Life, Intro to Biology" Eric Lander PhD. |
Integrative genomic and transcriptomic analysis of 775 human cancer cell line
Cancer: A. C. Villani (Broad): integrative genomic and transcriptomic analysis of 775 human cancer cell line #ASHG2103
— Dale Yuzuki (@DaleYuzuki) October 25, 2013
Abbott says FDA approved heart valve medical device
Abbott says FDA approved heart valve medical device http://t.co/ml6AWAv8my
— Reuters Health (@Reuters_Health) October 25, 2013
This video is what real #breastcancer awareness looks like #thinkbeforeyoupink
No pink in sight: This video is what real #breastcancer awareness looks like http://t.co/wCFGaZdo1c #thinkbeforeyoupink
— Veronica M. Combs (@vmcombs) October 24, 2013
Google Wants You to Live 170 Years
Google Wants You to Live 170 Years http://t.co/u8iHfC61AW
— Jean Michel Billaut (@Billaut) October 25, 2013
Steampunk Girl
Bastet Vamp http://t.co/xW68Td45Zg #Fashion #Steampunk #Steampunkgirl pic.twitter.com/o7T5y0cpx3
— Steampunk Tendencies (@Steampunk_T) October 11, 2013
Steampunk Michelin
Takanori Aiba http://t.co/Ykb41PAPJb #Sculpture #Architecture #Victorian #Michelin pic.twitter.com/7IG2SL2uOD
— Steampunk Tendencies (@Steampunk_T) October 14, 2013
Steampunkenstein
Steampunkenstein - Rick Baker I http://t.co/TesbZdoo63 #Halloween #Frankenstein #Steampunk pic.twitter.com/V6PLHh1toh
— Steampunk Tendencies (@Steampunk_T) October 22, 2013
The $40 Indian tablet that could help bridge America’s digital divide
The $40 Indian tablet that could help bridge America's digital divide http://t.co/rv7eJI9DPc
— Innovations (@innovations) October 23, 2013
The $40 Indian tablet that could help bridge America’s digital divide http://t.co/Izigz0hGOo
— Mitch Kapor (@mkapor) October 24, 2013
Eric Topol MD: "Digitizing life:hardware=proteins|cells; software=DNA"
J. Craig Venter: "gene patents are not a question of ethics but unaltered natural genes should not be patentable."
Digitizing life:hardware=proteins|cells; software=DNA @JCVenter On the era of digital biology|0,1,A,C,T,G convergence pic.twitter.com/CiQkqrVZUk
— Eric Topol (@EricTopol) October 19, 2013
- Thomas Goetz
co-founder at iodineI'm interviewing Craig this Friday in Berkeley. What questions should I ask?
-
Coste CatherineInnovation Geek, Marketing Assistant & WriterWell I'm curious about India... Seeing wonderful stuff there: they're printing good quality and cheap medicine out of 3D printers (!!), plus word is spreading that sequencing one's genome will soon be cheaper than car parking... Very curious about price of DNA sequencing in the US (23 and me and co.) and about these DIY bio garages booming worldwide... Are biohackers gonna disrupt big pharma? Will we use our DNA structure as signature (bank)?, like so: http://ethictransplantation.blogspot.fr/2013/08/the-gringotts-wizarding-bank-and-dna.html But I must confess I just started reading "Life at the speed of light", so... not sure about which questions I'd like to ask at this stage, sorry...Linked In, Digital Health group, Discussions about "Life at the Speed of Light: From the Double Helix to the Dawn of Digital Life" - J. Craig Venter
"Facial features are fine-tuned by noncoding DNA"
Facial features are fine-tuned by noncoding DNA http://t.co/7F2KIRi3SJ
— Guardian Science (@guardianscience) October 24, 2013
Fascinating paper on the #genomics of face http://t.co/9I16ZBRu30 Non-coding, enhancers play key role, w/long-range interX @sciencemagazine
— Eric Topol (@EricTopol) October 24, 2013
"Can Mobile Health Technologies Transform Health Care?"
Mobile technologies for health care--perspective http://t.co/5Pzf9AEQrl by @SteveSteinhubl and @EvanMuse @ScrippsSTSI @JAMA_current #mhealth
— Eric Topol (@EricTopol) October 24, 2013
Medical care anywhere via mHealth. Imaging of blood smears +, virtually anywhere with smartphone microscopy. http://t.co/b1H0RWW6tx #mHealth
— Steve Steinhubl (@SteveSteinhubl) September 23, 2013
 |
| Atul Gawande, MD: "Future of Healthcare Requires Constant Reinvention" |
http://jama.jamanetwork.com/article.aspx?articleID=1762473
the top 10 most exciting stories in #3dprinting
Don't miss the top 10 most exciting stories in #3dprinting in the last hour at http://t.co/qcpmVs8B9y
— B3dge (@Build3dprinter) October 24, 2013
100Kgenomes will position UK as a leader in genomic medicine by demonstrating clinical utility
Haga: #GenomicsEngland 100Kgenomes will position UK as a leader in genomic medicine by demonstrating clinical utility http://t.co/jVahJBoMw0
— Saskia Sanderson (@SCSanderson) October 24, 2013
"This 'Ending Cancer' stuff, while a laudable goal, is sending a wrong message to public "
This "Ending Cancer" stuff, while a laudable goal, is sending a wrong message to public @IBMWatson @MDAndersonNews pic.twitter.com/aJQh2CimmgSee the reactions and comments on Twitter... Very interesting!
— Eric Topol (@EricTopol) October 18, 2013
New Blog Post on Nanomedicine: Using ‘tiny little FedEx trucks’ to target breast cancer tumors
New Blog Post on Nanomedicine: Using ‘tiny little FedEx trucks’ to target breast cancer tumors http://t.co/dgzpe1VYq1
— TriLink BioTech (@TriLinkBioTech) October 7, 2013
NextCODE raises $15M for clinical genomics tech from Polaris and ARCH
NextCODE raises $15M for clinical genomics tech from Polaris and ARCH - Boston Business Jou... http://t.co/xfCCgPJIQf #biotech #genomics
— Bioinsilico (@bio_insilico) October 23, 2013
"Obtenez une seconde opinion médicale" avec SOmedical
 |
| http://www.somedical.com |
"Je ne sais pas quoi penser de ce site ? Nécessaire cependant.
Ayant expérimenté très récemment, à ma plus grande sidération, toutes les failles du 'fameux système de soins français' à l'occasion de la maladie terminale d'un proche.
Être malade, et puis un jour mourir, c'est une chose. Mais pas dans ces conditions. Pas en 2013.
'Obtenez une Seconde Opinion Médicale.
Êtes-vous certain d’être soigné par l’un des meilleurs médecins ? Les erreurs de diagnostic n’arrivent pas qu’aux autres ! Votre médecin n’est pas infaillible, il ne peut pas tout savoir sur les innovations thérapeutiques. Obtenir un second avis médical par l’un des meilleurs spécialistes mondiaux de la maladie qui vous concerne, c’est augmenter vos chances face à cette maladie !
C’est le rôle de SOmedical : identifier les meilleurs spécialistes en France, en Europe et partout dans le monde, pour vous. Ces Champions dans leur spécialité vous donneront leur diagnostic, et vous pourrez bénéficier des toutes dernières avancées médicales.'"
http://www.somedical.com/
Santech, éditeur de plateformes de e-santé
Connaissez-vous Christophe Lorieux from Paris ? Santech : éditeur de plateformes de e-santé... http://t.co/vKLw0uWge4
— Jean Michel Billaut (@Billaut) October 24, 2013
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| http://billaut.typepad.com/jm/2013/10/connaissez-vous-christophe-lorieux-from-paris-santech-.html |
Interview de Jean-Michel Billaut, président de l'Atelier BNP Paribas
Interview de Jean-Michel Billaut, président de l'Atelier BNP Paribas qui s'est vu décerner le Prix du Promoteur lors du Prix des Technologies Numériques 2011.
"How healthcare will drive semiconductors"
How healthcare will drive semiconductors http://t.co/2kez2WNyqa yes, the "super convergence" is coming @SIAAmerica
— Eric Topol (@EricTopol) October 24, 2013
Women: Here’s Your No. 1 Killer
Women: Here’s Your No. 1 Killer via @ClevelandClinic http://t.co/AX84HZ61w0 #heartdisease
— 23andMe (@23andMe) October 23, 2013
The completion of the 1000 Genomes Project
1000 Genomes just updated to the newest #Ensembl browser. Easy access to phase 1 integrated data @1000genomes http://t.co/RkvG9fmxdh
— Ensembl (@ensembl) October 23, 2013
@adamauton presenting poster today, The completion of the 1000 Genomes Project. 575W #ASHG2013 http://t.co/OciFJZhSGo
— The 1000 Genomes (@1000genomes) October 23, 2013
"Access to Patient-Level Trial Data — A Boon to Drug Developers"
Sharing individual patient data from clinical trials to catalyze new treatments http://t.co/Ol5ee6wqNJ @NEJM great last sentence #indivmedIt is ironic that the organizations that most resist wider access to data are the ones that stand to benefit so much from greater transparency.
— Eric Topol (@EricTopol) October 23, 2013
http://www.nejm.org/doi/full/10.1056/NEJMp1310771
Brain decoding: Reading minds
"By scanning blobs of brain activity, scientists may be able to decode people's thoughts, their dreams and even their intentions."
http://www.nature.com/news/brain-decoding-reading-minds-1.13989
DIgitizing the #brain http://t.co/fVFC1FePlp A lot more invasive than surgery @NatureNews #digitalhealth
— Eric Topol (@EricTopol) October 23, 2013
 |
| ILLUSTRATION BY PETER QUINNELL; PHOTO: KEVORK DJANSEZIAN/GETTY |
"Despicable Me 3? The MinION access programme is coming in November"
Despicable Me 3? The MinION access programme is coming in November http://t.co/vTvyj5LyTK via @pathogenomenick pic.twitter.com/kUxXMbclFR
— Portable Genomics (@portablegenomic) October 23, 2013
Scripps Translational Science Institute received $29M grant renewal to explore genomics, wireless tech and bioIT
Scripps Translational Science Institute received $29M grant renewal to explore genomics, wireless tech and bioIT http://t.co/UTBNbLKVQf
— Portable Genomics (@portablegenomic) October 23, 2013
Angelina, la science du génome humain et la théorie de la démocratisation de la santé
A mon avis, faudrait Angelina Jolie pour expliquer ceci (entre autres) aux Français : préférez-vous donner vos organes ou vos données génétiques ? Moi, c'est mon prof de génomique qui me l'a expliqué au MIT à Boston, USA, avec l'exemple de la mucoviscidose :
Would you rather donate your data, or your lungs?
http://ethictransplantation.blogspot.fr/2013/10/would-you-rather-donate-your-data-or.html
Angelina, première preuve de la démocratisation de la santé, selon Eric Topol, cardiologue et généticien américain, auteur de l'ouvrage intitulé "The Creative Destruction of Medicine"E Topol: "Angelina Jolie is the exemplar case of democratizing medicine."
http://ethictransplantation.blogspot.fr/2013/10/e-topol-angelina-jolie-is-exemplar-case.html
Pendant ce temps, en France, il est interdit au citoyen lambda de demander le séquençage de son génome ... A mon avis (et à écouter mes profs au MIT), Angelina a eu des infos que les Français n'ont pas ... Et moi, à force d'écouter mes profs au MIT (et à la Harvard Medical School, les deux établissements d'enseignement ne sont pas très éloignés l'un de l'autre, tous deux dans la région de Boston, MA, USA), je commence aussi à avoir des infos que les Français n'ont pas ... Mais ...1) Je ne suis pas Angelina Jolie
2) Je ne vis plus en France
Euh ... quelqu'un a-t-il une connexion avec Angelina Jolie ? (sa "petite" famille vient en France pour les vacances, je crois ...)
"Are We Puppets in a Wired World?"
Are We Puppets in a Wired World? http://t.co/X1b8iiZ3bS @nybooks On the downside of digital disruption
— Eric Topol (@EricTopol) October 23, 2013
 |
Are We Puppets in a Wired World? |
The Beard-ome
 |
| From the science-for-fun department: |
The FUNNIEST Science Video On The Web! This is by far one of the funniest scientific-genre videos on the web http://t.co/gfGYMTRNs5
— Americanbiotech (@americanbiotech) October 23, 2013
NIH-funded researchers show that "different Cancers Can Share Genetic Signatures"
NIH-funded researchers: "Even when cancers originate from different tissues, they can show similar features at the DNA level."
From
the NIH Director's Blog: NIH-funded researchers recently compared the
genomic fingerprints of tumor samples from nearly 3,300 patients with 12
types of cancer discovering that even when cancers originate from
different tissues, they can show similar features at the DNA level.
Learn More: http://
 |
| http://directorsblog.nih.gov/2013/10/22/different-cancers-can-share-genetic-signatures/ |
Learn More: http://
Welcome to the era of "biological teleportation"
 |
| http://www.quickmeme.com/meme/3rjdr3/ |
Jean-Michel Billaut, a digital economist: "Hébé ... Cela va loin ... Balader des bouts d'ADN sur le net , imprimer des cellules humaines ou des médicaments ..."
Craig Venter’s ‘biological teleportation’ device http://t.co/Ws6mhNBQc8
— Jean Michel Billaut (@Billaut) October 23, 2013
Video Tip of the Week: GenoCAD, computer-assisted design for synthetic biology
Video Tip of the Week: GenoCAD, computer-assisted design for synthetic biology http://t.co/eHsiacds9i #bioinformatics #synbio
— OpenHelix Staff (@OpenHelix) October 9, 2013
"There are a thousand no's for every yes"
 |
| http://www.strangeling.com/maritimesunset.html |
The Unsustainable Economics of Cancer Drugs: “The first physician-initiated revolt" against high cancer drug prices
The Unsustainable Economics of Cancer Drugs: “The first physician-initiated revolt" against high cancer drug prices. http://t.co/hfBnrnu4nD
— freakonomics (@freakonomics) October 22, 2013
Your weirdest lab rat session ever
Only in Australia: Possum found in an bakery; it had eaten so many pastries, it couldn't move. pic.twitter.com/ETMxGRiRN9
— Wilson da Silva (@wilsondasilva) October 22, 2013
Bringing biotechnology in to the home: Cathal Garvey at TEDxDublin
Cathal Garvey is the creator of the blog Indie Biotech, his personal endeavour to provide tools, materials and learning resources for biotechnology to individuals worldwide. Worldwide, the DIYbio movement is taking hold and generating renewed interest in community biotech. Cathal provides affordable, Open-Source-DNA development platforms, kits and strains for beginners to learn the engineering of bacteria easily, and perhaps later to facilitate engineering of plants and simple bugs such as Sea Monkeys. He hopes to change the face of biotech, and perhaps change some lives for the better in the process.
@onetruecathal Thank you Cathal 4 your outstanding TEDx Dublin presentation 'Bringing biotechnologiy in to the home'! http://t.co/TBwdI4dG39
— CATHERINE COSTE (@cathcoste) October 22, 2013
"The Genomic Oracle", a highly informative article
If your DNA is sequenced at birth, how would if affect your life? A new project aims to find out. http://t.co/AJPGVXba1X
— Portable Genomics (@portablegenomic) October 22, 2013
The Genomic Oracle by @carlzimmer http://t.co/mGQQBzYhpL Sequence newborns? Only after M's indiv have been -->informative, value #indivmed"The cost to sequence an entire genome is still substantially higher, at several thousand dollars. A few clinics in the United States are starting to sequence the full genomes of patients whose diseases can't be identified by the standard battery of genetic tests, or whose diseases resist conventional treatments."
— Eric Topol (@EricTopol) October 21, 2013
http://www.slate.com/articles/health_and_science/human_genome/2013/10/babyseq_genome_study_will_sequencing_dna_at_birth_change_someone_s_life.html
In India, people are spreading the word that sequencing your genome will soon cost less than parking your car...
Breaking an arrhythmia guided by smartphone ECG
Breaking an arrhythmia guided by smartphone ECG pic.twitter.com/alRDozg52s 17 yo responds to @djsammy8 CSM @AliveCor via @DrDave01 #mHealth
— Eric Topol (@EricTopol) October 22, 2013
#ionworld2013
#ionworld2013 buzzz is out! http://t.co/VSqomau8sc
— SeqComplete (@SeqComplete) October 21, 2013
Wang: Protons to be installed:2 Shenzhen, 31 China, 5 US, 1 Europe. #ionworld2013
— Dale Yuzuki (@DaleYuzuki) October 21, 2013
#ionworld2013 Milan Radovich: "Protons win Championships in triple negative BrCa sequencing" - awesome!
— jonathan day (@DayJday1022) October 21, 2013
Allcock: "The sequencing is helping define diagnosis. And this is really powerful." #ionworld2013
— Dale Yuzuki (@DaleYuzuki) October 21, 2013
Next up: Richard Allcock, Royal Perth Hospital Univ. Western Australia Perth #ionworld2013
— Dale Yuzuki (@DaleYuzuki) October 21, 2013
UWA's Richard Allcock is on stage talking about all the sequencing he does across his many platforms #ionworld2013 pic.twitter.com/7ChbwjkNdt
— Ion Torrent (@iontorrent) October 21, 2013
Allcock: Have taken 336 genes covering multiple diseases, targeting 1.9Mb Neuromuscular disease, also neg's from other group #ionworld2013
— Dale Yuzuki (@DaleYuzuki) October 21, 2013
Richard Allcock describes his lab's role as critical nexus between research and diagnostic #ionworld2013
— Brent Applegate (@BrentApplegate) October 21, 2013
Wang: NIPT in China - 20M newborns/year there. T21, T13, T18 screens on Proton. #ionworld2013
— Dale Yuzuki (@DaleYuzuki) October 21, 2013
Wang: Glioblastoma (GBM) looking at intratumor hetergeneity, RNA-Seq first, very consistent metrics, up/down reg. genes #ionworld2013
— Dale Yuzuki (@DaleYuzuki) October 21, 2013
Claritas CEO Patrice Milos speaking about gene panels and exome sequencing #ionworld2013
Claritas CEO Patrice Milos speaking about gene panels and exome sequencing #ionworld2013 pic.twitter.com/QDmUy5suyI
— Ion Torrent (@iontorrent) October 21, 2013
"E Topol: Angelina Jolie is the exemplar case of democratizing medicine."
“@DaleYuzuki: E Topol: Angelina Jolie is the exemplar case of democratizing medicine. #IonWorld2013” pic.twitter.com/Sjvu7lQ7WA
— Eric Vennemeyer (@evennemeyer) October 21, 2013
The famous #ionbus at #IonWorld2013 #Boston
The famous #ionbus at #IonWorld2013 #Boston pic.twitter.com/00AcYo2Z3f
— Novogen (@NovogenMexico) October 21, 2013
"We have discovered the secret of life!"
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| Leonor Fini, Lithography. |
And you can make the Cs fit with Gs, and get three hydrogen bonds.
And they would fit perfectly into a double helix if the two strands were running in the opposite direction, and would nicely reproduce the spacing evident in photograph 51 and the dyad symmetry present in that.
And Crick comes into the lab about an hour later.
Watson shows it to Crick, and Crick instantly realizes, this feels like an answer.
Not this other thing you were doing a few days ago, Jim.
This feels good.
Watson is still cautious-- because they've already blown it before in producing the wrong structures-- and really wants before they tell anybody to have the machine shop build a careful model of DNA to show that the whole thing will really work.
And as partnerships go, they go to lunch at the Eagle Pub.
And although Watson says, let's not tell anybody yet, Crick sits down at the Eagle Pub and announces to anyone who will hear, 'we have discovered the secret of life!'.
And as it turns out, they had.
Because it turns out that when the model was carefully built, the model checks out." 7.00x Intro to Biology- The Secret of Life Eric Lander PhD. "DNA Structure: the Race".
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| Crick and Watson's DNA molecular model, 1953. |
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| http://www.anselm.edu/homepage/jpitocch/genbio/doublehelix.JPG |
Why is this model so good?
It isn't just that it explains the X-ray crystallographic data. It isn't just that it explains Chargaff's Rules (A-T and C-G having same ratios). A model that has A matching T, G matching C, Cs matching Gs, Ts matching As-- a model that does that has one amazing property. It explains something.
It explains heredity.
It explains heredity because each of those strands alone is a complete template for the other strand. If I give you one strand, AGCTAAGG, you can fill in the other strand. If I separate these two strands, each can be used as a template to make a copy of that information. That is a stunning observation. Suddenly, the whole notion of how you can replicate information is clear. You replicate information by having a double helix where the information is fully specified on either of the two strands. You peel them apart, and you can put together two double helices. This is how chromosomes will replicate. This is what mitosis and meiosis must be about-- the transmission of genetic information. That's why Chargaff's Rules matter.
That's why Crick goes into the Eagle Pub and he says, 'we've discovered the secret of life!'."
7.00x Intro to Biology- The Secret of Life Eric Lander PhD. "DNA Structure: the Race".
Breast Cancer Is Not a Facebook Status Game
RT @DrSusanLove: @lisaadams Great post! Breast Cancer Is Not a Facebook Status Game, @HuffPostWomen - http://t.co/899Nfc9Ufd
— Elaine Schattner (@ElaineSchattner) October 20, 2013
"Girl smuggled into Britain to have her 'organs harvested"
Seriously horrible.RT @picardonhealth: Girl smuggled into Britain to have her 'organs harvested," by @Steven_Swinford http://t.co/SiBcQT7Pk8
— Elaine Schattner (@ElaineSchattner) October 20, 2013
Biosensor overdose in baby monitoring
Bringing Up Baby and Fretting About Vital Signs. Too much vigilance in the crib with new monitors, gadgets? http://t.co/pttwfGIdns
— Laura Landro (@LauraLandroWSJ) October 21, 2013
The Cancer Drug Racket
New drugs could extend cancer patients’ lives—by days. At a cost of thousands and thousands of dollars. Prompting some doctors to refuse to use them.
On the cover, @NYMag: 'The Cancer Drug Racket' - http://t.co/ql6zPuIpcD pic.twitter.com/ZKxxgbaPl4
— Elaine Schattner (@ElaineSchattner) October 21, 2013
"The 0 gravity economics of #cancer" meds http://t.co/lBZGS7HEHH "the only check on the system is corporate chutzpah" via @ElaineSchattner
— Eric Topol (@EricTopol) October 21, 2013
"Adrian, humain 2.0" par David Angevin et Laurent Alexandre
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| Amazon |
"L’Europe bioconservatrice est devenue un 'Jurassic Park industriel', ruiné par la crise. Le 'G2 transhumaniste' Etats-Unis-Chine règne sur la planète grâce à son avance dans les 'NBIC' (Nanotechs, biotechs, informatique, sciences cognitives). Et, dans l’ombre, un 'Prince des ténèbres' tire les ficelles : l’überpatron de Google, Sergeï Brin." Libération, 12 mai 2013. Cette fiction au langage cru, façon tripot, rappelle étrangement le propos du livre "Les Morts ont tous la même peau" écrit par Boris Vian en 1947. Cet ingénieur avait fait le pari de "pondre" un chef d’œuvre en 48 heures ... Situé dans une Amérique raciste et faussement puritaine, le roman intitulé "Les Morts ont tous la même peau" raconte l'histoire de Dan, un sang-mêlé (un noir à peau blanche) ayant réussi à se faire une place dans la société des blancs sans que ceux-ci ne sachent rien de ses origines. Sa vie était parfaite jusqu'au jour où un homme disant être son frère vient lui réclamer de l'argent en le menaçant de raconter aux gens ses vraies origines. Menacé, Dan assassinera 'son frère', allant au-devant de graves ennuis et d'autres crimes. (Source : Wikipédia). Dans les deux cas, les auteurs font les vendanges du sordide afin de tendre l'ultime miroir (grand cru vendanges tardives) à une société en faute : celle prônant le racisme (sous couvert de puritanisme) aux USA durant la première moitié du XXème siècle ; celle condamnée à suivre les Google et autres Amazon faute d'alternatives, tant il est universellement reconnu que l'Europe n'est pas la panacée des startups ou de l'innovation ... Les anglicismes foisonnent chez "Adrian, humain 2.0" à l'instar des obscénités de bordel "underground" dans "Les Morts...". On comprend que "l'exception culturelle" de l'Europe en général et de la France en particulier (ayant fini par crever de son principe de précaution inscrit dans sa constitution), c'est du "bullshit". De là à ce que les auteurs viennent cracher sur le tombeau d'une Europe qui a raté tous les virages, celui de l'innovation, du progrès humain ... et que ces crachats éclaboussent quelques transhumains dégénérés au passage ... il n'y a qu'un pas, que le tandem Angevin-Alexandre franchit, tout comme l'avait fait Boris Vian à son époque. Voulons-nous comprendre le message ? Non. Nous ne voulons pas comprendre que le généticien Laurent Alexandre crache sur les fossoyeurs de l'innovation. On imagine à quel point le chef d’œuvre de Boris Vian, "Les morts ont tous la même (couleur de) peau" a fait scandale lors de sa parution en 1947 ... En 2013, l'Europe en général et la France en particulier boudent l'innovation. Sous couvert de puritanisme. Cela fait les choux gras des Google et autres Amazon. Faut-il vous faire un dessin ? Eh bien, il me semble que c'est ce que fait ce livre, non ?
PS aux deux auteurs : la couv' de votre bouquin est nulle à chier ... vous vous êtes fait avoir par votre éditeur papier (typique : lisez donc Ape de Guy Kawasaki et vous comprendrez pourquoi).
Rochelle and the Keystone Cops
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| Former French President Sarkozy and President at present Hollande |
Dupont et Dupond... manque le pendule, les cannes, mais y'a déjà les talonnettes.. pic.twitter.com/hEjzZJyZ
— Jean Michel Billaut (@Billaut) May 13, 2012
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| Er, since you're asking, yes, I'm French...but I'm leaving my country... http://www.deviantart.com/art/Monster-High-Rochelle-Goyle-323601184 |
"DNA Structure, the Race"
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| http://boingboing.net/2012/11/08/the-turn-of-the-screw-james-w.html |
The ornithologist--erstwhile ornithologist in college-- one James D. Watson, and the physicist, working in the admiralty during World War II, Francis Crick.
And Watson came over on a fellowship to the Medical Research Council labs in Cambridge, England, and was there to work on structures of things with Francis Crick, who knew a lot of crystallography, knew mathematics and crystallography.
And they were incredibly well known around the Medical Research Council because they talked a lot and did very little. They did a lot of talking. And they had big ideas about what they were going to do, including this DNA thing. They knew this was really important.
They weren't supposed to be working on DNA.
They were supposed to be working on something else. The distinguished head of the lab, Sir Lawrence Bragg, didn't want them working on DNA because King's College down in London was supposed to be doing the DNA stuff. But you know how kids are. They really wanted work on this DNA stuff. And they made some models. And they were kind of crazy models. And some of them were kind of embarrassing models in 1952 that they were making that anybody could have seen they had it wrong and so on. They began going down to King's College and talking to Rosalind Franklin, who was working on crystallizing and doing X-ray diffraction patterns on DNA, invited there by Maurice Wilkins.
The two of them didn't get along.
Rosalind didn't really have anybody to talk to about her stuff, and there was a bit of tension between them due to a bunch of misunderstandings. Crick and Watson came down and made a pain of themselves.
And they talked back and forth. And Rosalind Franklin hated all this abstract models stuff. She wanted hard data. Crick and Watson loved models. And you had this tension back and forth there.
Rosalind Franklin, at one point, was sure, based on her data from one form of DNA, that DNA was certainly not a helix, she even published a death announcement, a black-rimmed paper saying the death of the helix, saying that it certainly wasn't going to be a helix.
And it was back and forth.
And it was sort of comic.
At the beginning, in 1952, it had a feeling of Keystone Cops to it in a way.
And you've got to read Jim Watson's autobiography The Double Helix because he tells these stories."
7.00x Intro to Biology- The Secret of Life, Eric Lander PhD.
"New iPad publishing system Prss sets out 'to make print feel stupid'"
New iPad publishing system Prss sets out 'to make print feel stupid' http://t.co/jPGo6LiAAK
— Jean Michel Billaut (@Billaut) October 21, 2013
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