Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


Is The Digital Health Industry About To Fail?

An Open Letter from the GetHealth Team:

"Dear mHealth Industry, Quantified-Self Movement, and Champions of Big Data,
As you are no doubt aware, there has been a recent proliferation of mobile apps, wearable devices, and patient services which allow us to measure and track our daily health behaviors. In a world where so many problems are caused by unhealthy behaviors, the popularity of such products has come to be seen as the future of personal health: the panacea to our chronically unhealthy and overweight society.
We now have access to seamless, reasonably affordable technology that can track how many steps we take, the quality and duration of our sleep, how many calories we burn, and even our blood pressure and mood levels. Never before have we been able to gain such detailed levels of real-time data concerning our health-habits.
This industry operates under the belief that the more aware we are of the details of our daily behaviors, the better position we are in to make the changes necessary to improve our health and lifestyle.
On this view, information is the key to change. The more data we have about how much we move, eat and sleep, the more we can control and alter these numbers to become healthier and happier individuals.
However, while these devices do mark a new and interesting direction for personal health, they fall way short of offering true value to the user as they currently stand."



...keep the data in the background and reveal the insight.

Read more here: http://blog.gethealthapp.com/post/63681783790/why-the-digital-health-industry-is-about-to-fail#.UmKjrBBo_E8..."While I don’t agree that digital health will fail, they make a good point about the need to focus on the result and not the data. Far too many digital health startup companies worry too much about the data and not enough about what people do with the data. It makes sense why. The later is much harder to do. However, that’s also what makes doing the later so much more valuable."

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