Precision Medicine will need to get out of the pharma silo that is based on symptoms

Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!

Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.

After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Doomsdare, a medical thriller (action taking place in Beijing) Fall 2016; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2017). Special thanks to Prof. Emmanuel Lincot, lawyer David Kilgour and Isabelle Provost for their help.

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC ( to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (

Genomic Musical Hitting Broadway!
How well do you know your genes, and what do you know about the major discoveries about the human genome? Think gene sequencing, gene therapy, computer programming to translate RNA (the messenger of DNA) into protein sequences, 3D bioprinting -- that is, printing out of a 3D printer, human biological material -- and bioinformatics and DIY bio are science material that has nothing to do on stage on Broadway?

Well, don't be so sure... Oh, and by the way...

Do we own our own body (and genes and organs?)

Medicine and science are enhancing and transforming mankind (homo sapiens). We read about this in the paper everyday, worldwide. It's happening now, right under our feet...

The musical about the Human Genome Project I'm working on is about people and who owns them, about cyberpunks, bio hackers, DIY Bio, biotechs and "pig" pharma. Digital devices, sensors, big and small data, genomics, 3D printing, bioengineering, organ replacement technologies (and donation and trafficking): what do WE THE PEOPLE have to say (and sing) about this?

 Possessus, from the Latin word meaning both possessing and possessed.

This Facebook page "Homo Possessus" is aimed at knowledge sharing for all and by all, so your contribution is welcome and wanted!

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