Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Doomsdare, a medical thriller (action taking place in Beijing) Fall 2016; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2017). Special thanks to Prof. Emmanuel Lincot, lawyer David Kilgour and Isabelle Provost for their help.

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


Eric Topol MD: "Digitizing life:hardware=proteins|cells; software=DNA"

J. Craig Venter: "gene patents are not a question of ethics but unaltered natural genes should not be patentable."
  • Thomas Goetz
    co-founder at iodine
    I'm interviewing Craig this Friday in Berkeley. What questions should I ask?

  • Innovation Geek, Marketing Assistant & Writer
    Well I'm curious about India... Seeing wonderful stuff there: they're printing good quality and cheap medicine out of 3D printers (!!), plus word is spreading that sequencing one's genome will soon be cheaper than car parking... Very curious about price of DNA sequencing in the US (23 and me and co.) and about these DIY bio garages booming worldwide... Are biohackers gonna disrupt big pharma? Will we use our DNA structure as signature (bank)?, like so: http://ethictransplantation.blogspot.fr/2013/08/the-gringotts-wizarding-bank-and-dna.html But I must confess I just started reading "Life at the speed of light", so... not sure about which questions I'd like to ask at this stage, sorry...
    Linked In, Digital Health group, Discussions about "Life at the Speed of Light: From the Double Helix to the Dawn of Digital Life" - J. Craig Venter

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