Precision Medicine will need to get out of the pharma silo that is based on symptoms

Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!

Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.

After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC ( to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (

Genomic Musical Hitting Broadway?...

Today I asked famous musical singer Ramin Karimloo ("The phantom", "Les Miz"...) if he was ready for that: Genomic Musical hitting Broadway! Genomic Entertainment is emerging in California, as genomics (the science of human genes) is happening right under our feet and disrupting medicine as we know it... Talking of bioinformatics, or about  becoming a chemical engineer...

Ramin: "Going to see my high school chemistry teacher today. Can't wait. Will have to gently tell her I never became a chemical engineer though."

Me, to Ramin: Would you consider a lead role in a genomic musical, though, as this would reconcile both (singing and science)? Genomic musical hitting Broadway - soon...
On Genomic Entertainment: Patrick Merel, Founder of Portable Genomics, LLC, La Jolla, CA, a company developing a new concept for "the visualization and use of genomic data on portable devices. To bring genomic personalized and preventive medicine onto smartphones. Anticipating the $100 genome era and the P4™ medicine revolution (Predictive, Personalized, Preventive, Participatory). Incidentally, developing mobile applications in the upcoming field of Genomic Entertainment and serious gaming. (...). Molecular Diagnostic expert with European and US market experience. Automation specialist in molecular methods for diagnostic, genome sequencing and screening for biomarkers discovery." (Source).

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