Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


"Success story: my genes and yours". French Touch Genetics and the "Good Bye Lenin!" attitude


French touch genetic: "Good Bye Lenin!"
"Success story: my genes and yours"

"'Gamete donor selection' is just another way to say 'sexual selection'. 'Genetic calculation' extends the evaluation of the expected phenotypes using tools that weren’t available until recently. And better understanding of the genotype/environment/phenotype relations can help to improve the fitness of our descendants. (...)  

I’m happy that 'genetic discrimination' is illegal, at least in some countries around the world. This is the case for the USA were the state was wise enough to install GINA, to keep GATTACA in the science-fiction realm. Because GATTACA is essentially about discrimination.
Others states prefer the chicken/ostrich attitude: afraid of the innovation, dealing with it as if they were able to stop it, the head deep in the ground, unaware (or acting as if) that their citizen have access to DTC genetic tests (DNA travels quite well) and already some of them have bough them. France is an example of a state that made illegal DTC genetic testing."

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