Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Doomsdare, a medical thriller (action taking place in Beijing) Fall 2016; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2017). Special thanks to Prof. Emmanuel Lincot, lawyer David Kilgour and Isabelle Provost for their help.

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


Would you rather donate your data, or your lungs?

"Intro to Biology, The Secret of Life", MITx 7.00, Eric Lander PhD (MOOC)
"5% of all individuals are carriers for cystic fibrosis. Could be worth couples testing to know if they are carriers for cystic fibrosis, for example.  Suppose you were a carrier for cystic fibrosis. What's the chance that you are going to meet someone and they'll also be a carrier for cystic fibrosis? 1 in 22. 1 in 22 is a 5% chance. So that means somebody who knew that she was a carrier for cystic fibrosis knows that there's a 5% chance that the person they might marry will be a carrier for cystic fibrosis. These are actually meaningful numbers in the population, things people might want to know."  (Eric Lander, PhD, "Intro to Biology", lecture week 4: "Basics of Human Genetics")

And remember: a transplant is not a cure. Though it can help you live longer... So, which one would you rather donate? Your data, or your lungs?...

==> http://65redroses.livejournal.com/134498.html

1 commentaire:

Low-Coste Innovation Blog a dit…

Pour rappel : la loi française interdit au citoyen français de faire séquencer son génome. Puis-je suggérer à nos aimables institutionnels de l'agence de la biomédecine de suivre ce MOOC d'Eric Lander ? C'est passionnant, on apprend plein de choses (si si)...