Precision Medicine will need to get out of the pharma silo that is based on symptoms

Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!

Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.

After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC ( to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (

All you need to know about me (author of this blog)...

I live in New-Zealand (Wellington and Auckland), where I work as a (Wellywood) scenarist and I do have a passion for trees and forests... and books... My family are scattered around the world, which I guess makes me a frequent traveller (thank you Emirates Airlines!): NY, Malaysia (Kuala Lumpur, Ipoh), Monaco and Provence, Berlin (well I haven't been in Germany for a while, actually...)

I'm just another passionate story teller (plenty of us all around the world)... Love telling other people's story (mine is too ordinary)... Surrounded by geeks, I do have plenty to tell... Imagine that Indian guy from "Life of Pi" - er actually I'm only that narrator guy - living with Big Bang Theory's Leonard and Sheldon...

French-born; in love with languages... and words... My favorites languages are English and oral Mandarin Chinese... I'll need another life to learn how to write Chinese characters... well I do recognize a few, but... Ended up as a Post-Graduate in German literature just because I was fascinated by books by Thomas Mann and other German "romantic" authors...

My favorite obsessions:
- browsing bookshops all around the world, in megacities and smaller towns... taking snapshots of books with my iPhone (book covers, that is) until I'm told: "Please, no more photos..." - or, on a couple of occasions: "Thank you for loving books so much": Blackwell's in Oxford, UK and Kinokuniya Malaysia in Kuala Lumpur, Mr. B's Emporium of Reading Delights in Bath, UK, or Librairie le Phénix, Paris, Whitcoulls in Auckland-Henderson...
- listening to soundtracks of "Musicals"... Like "Memphis", "The Phantom of the Opera", "Love Never Dies", "Once", "The Book of Mormon", "Monkey King", "Les Miz", "Chicago", "Wicked"... I'm fascinated by interpretes, and by TV shows on innovation, like Disney's Phineas and Ferb...

Most of all, I like sharing and positive thinking... Well, that's all folks!

YOUR e-mails are always welcome! Please send them at

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Low-Coste Innovation Blog a dit…

Tree in Matamata, near Hobbiton (NZ).