Precision Medicine will need to get out of the pharma silo that is based on symptoms

Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!

Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.

After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC ( to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (

An Apple TM a day keeps the doctors away...

...or can bring patients and doctors together...

"What can Apple bring to the table, er, wrist, that Timex and any one of hundreds of cheap watches don’t already provide consumers?
That’s the question Harvard Business Review’s H. James Wilson asks today, and he comes up with a fascinating answer.
The iWatch, he says, won’t actually be a watch at all.

'Using evidence and a bit of logic,' says Wilson, 'I bet the iWatch will be much less a time piece and much more platform for auto-analytics and managing yourself.'
He points to the growing trend of devices on Apple Store walls that actually measure our own bodies, tracking our stats, and other wearable tech. There are things like Fitbits, Nike Fuelbands, and iHealth scales and blood pressure monitors hanging right up there with the earpods, iPhone cases, and (yes) iPod nano wristwatch bands.

Apple’s strength in designing products that we don’t even know we need lies in its ability to simplify complicated sources of information into a cohesive display or operating system. There are a ton of analytics floating about out there, including our schedules, our contacts, our health data, and our connections to other people. Imagine putting all of these sources of info into one place. With an iWatch, says Wilson, Apple can do the same thing, can 'make users’ experience of time more intimate by tying it to who they are and what they care about.'"

And to their health profile...

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