Precision Medicine will need to get out of the pharma silo that is based on symptoms

Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!

Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.

After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC ( to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (

Avatar and The Hobbit: Kiwis teaching sustainable development to China?

What do Peter Jackson (Lord of the Ring Trilogy, The Hobbit) and James Cameron (Titanic, Avatar) have in common? Both are willing to teach the Chinese nation, which economy is to become worldwide leader, how to do (and especially not to do) a few things, such as: trash the planet (and the people). Both are doing it from Wellington, New Zealand. Actually, this country kind of sets the example when it comes to see eco freaks (talking about earth health) at work...

China and New-Zealand couldn't be any more different...

... though Chinese people and Kiwis do have that one thing in common: they are a Nation of farmers. Peasants. Once you've established this, all you can talk about are... differences... There's a huge gap between both countries: Chinese folks love noise (supposed to make evil spirits leave) and big crowds, they love to rush, they couldn't care less about ecology. Earth health is not an issue for them. They don't give a flying freck... In New-Zealand, people love to take their time, they also find it highly enjoyable to contemplate a beautiful and quiet landscape... They are all about sustainable farming... Eco freaks... Earth health and sustainable development are top priorities here (throughout the country)...

So when Gandalf the Grey seeks Bilbo Baggins the Hobbit to take him on an adventure, Bilbo reacts just as the average Kiwi (New-Zealander) would: he claims the Dwarfs (Chinese) crowd him, he wants to be left alone so that he can carry on enjoying his peaceful daily routine... instead of helping the Dwarfs fight a terrible dragon... Dragon? ok, talking here about what China is doing in Africa, or has done in Darfur, totally means crossing red lines... Although... The Dragon can be seen as a parable: China's economy will lead the world, ok, fair enough, I guess... Fair? Behind the hype, we can clearly see various and serious problems (a well-known fact: problems are able to cross land borders and all other boundaries in a world gone global)... Human rights, forced labour, death penalty, pollution (sickening fogs and polluted rivers, poisoned food as a result of corruption), just to name a few... What our modest but smart little Doctor Watson-Kiwi-Hobbit will eventually do is: join the quest, in order to help ... fight the dragon. Thanks to Gandalf's mediation... or should I say, Cameron's and Jackson's...

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