Precision Medicine will need to get out of the pharma silo that is based on symptoms

Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!

Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.

After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC ( to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (

What are your own genes? Something you don't own

"You Don't 'Own' Your Own Genes: Researchers Raise Alarm About Loss of Individual 'Genomic Liberty' Due to Gene Patents: "

"Just as we enter the era of personalized medicine, we are ironically living in the most restrictive age of genomics. You have to ask, how is it possible that my doctor cannot look at my DNA without being concerned about patent infringement?

The U.S. Supreme Court will review genomic patent rights in an upcoming hearing on April 15. At issue is the right of a molecular diagnostic company to claim patents not only on two key breast and ovarian cancer genes -- BRCA1 and BRCA2 -- but also on any small sequence of code within BRCA1, including a striking patent for only 15 nucleotides." (Source).

Jean-Michel Billaut (@nthropologist) :  "On pourrait dire que ce qui se passe aux USA ne nous concerne pas. Le problème c'est que les gènes des Américains sont les mêmes que les nôtres à 99,5 %... donc si un brevet mondial est pris sur le gène XXXX sur le chromosome 4, que se passe-t-il pour les Gaulois ? Les Homo Sapiens qui vivent sur le territoire américain ont 99,5% de gènes identiques aux Homo Sapiens qui vivent en Europe et en France... Comme ils sont beaucoup plus en avance que nous (désolé) ... ils vont créer des médicaments 'génétiques' pour guérir le cancer, Parkinson, etc. Médicaments que le Gaulois évolué pourra acheter sur Amazon avec 'un DRM' américain (Digital rights management)... Je ne sais pas si vous vous en rendez compte ... mais les nations dans quelques années ..." (Facebook, 27/03/2013).

Aucun commentaire: