Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


Doctors and Data: United We Stand?

Oh, medical data, cool. But hey, wait a minute! Who should be entitled to see it, access it, share it, work on it, etc.?

The sequencing of genome (genes) is triggering a revolution in health. Some physicians say we are now facing an upcoming "genotsunami" only few of us are aware of ... yet in a very near future this "tsunami" will become... unmissable. I guess most doctors see this as a burden... what's more, an unfair one. "Genotsunami" doesn't sound deceptively chirpy, does it? Aren't we talking about great prospects here? Gaining quality of life, years of life, all thanks to the marvels of genomics... Now I sound deceptively chirpy...  Nobody can tell the future of medical science for sure, but there's one thing I can tell for sure 'cause I've been around doctors a lot: they are not into data. Data is for secretaries, or for geeks. Not for Doctors. Now my wild guess is that we're going to have a problem here, 'cause cutting edge medical science is all about data. Global data, that is. (I know I'm only making things worse here, talking about Big Data). If you're not convinced, well why not check this out for a start...

"Big data and DNA: What business can learn from junk genes":

==>  http://gigaom.com/cloud/big-data-and-dna-what-business-can-learn-from-junk-genes

So we should induce a (major) change of mentality. (Big) Data is so beneath doctors, you see...

Inducing a change of mentality can be such a pie-in-the-face job... 

Now I might want to take a look at that new book by Luc de Brabandère, co-founder of "the world's leading advisor on business strategy" Boston Consulting Group: "Corporate Words and Things" ("Les Mots et les choses de l'entreprise") ...

"Les mots et les choses" : résumé en français 

"Comment conduire le changement en entreprise si l’on ne comprend pas le changement, comment créer, développer ou révolutionner un 'business model' si l’on ne comprend pas ce qu’est un 'modèle mental', comment mener une 'réflexion stratégique' si l’on ne s’est jamais demandé ce qu’est réfléchir, penser et imaginer, s’étonne à juste titre De Brabandere.
Voilà donc un livre passionnant et exigeant, qui n'a pas pour vocation d'apporter des réponses, mais bien d'ouvrir les questions fondamentales. Voici donc un plongeon aux sources de la pensée dans un monde où l’acte même de pensée est remis en cause par les nouvelles technologies de l’information : 'Toute idée devra-t-elle bientôt tenir en 140 caractères' (page 95) ?
S’interrogeant sur les liens entre 'management de la connaissance' et l’ignorance, l’auteur nous propose une définition originale de la créativité : 'l’aptitude à gérer l’ignorance' (page 18). Il nous demande : 'Savez-vous ce que vous ne savez-pas ?'. Plus loin, il nous rappelle que la pensée créative, 'c’est la pensée qui échappe à la logique' (page 83), et qu’il convient de 'définir l’innovation comme un changement de la réalité et la créativité comme celui de la perception' (page 85).
Voici une lecture stimulante, à la croisée de la philosophie, de la psychologie, de la linguistique, des sciences cognitives, du management, de la créativité et de l’innovation, le tout parsemé de bon sens et de traits d’humour dont Luc De Brabandere a le secret."


1 commentaire:

Catherine a dit…

Pic with birds: "Medical Humour" on FB.