Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


Que se passe-t-il lorsqu'un chirurgien cesse de progresser ?

Un chirurgien qui cesse de progresser est-il au sommet de son art ? Ou a-t-il faux sur quelques points essentiels ?

Ne manquez pas cette chronique bioéthique de l'incomparable Atul Gawande, chirurgien écrivain, auteur de Bestsellers et chroniqueur au New Yorker ... "Personal Best: Top athletes and singers have coaches. Should you?"

Nous n'avons pas l'équivalent d'une telle personnalité en France ... Voyez plutôt ce qui suit ... impressionnant ...

"Atul Gawande is a surgeon, a writer, and a public-health researcher. He practices general and endocrine surgery at Brigham and Women’s Hospital, in Boston. He is also a professor of surgery at Harvard Medical School and a professor in the Department of Health Policy and Management at the Harvard School of Public Health.
His research work currently focusses on systems innovations to transform safety and performance in surgery, childbirth, and care of the terminally ill. He serves as the lead adviser for the World Health Organization’s Safe Surgery Saves Lives program, and is the founder and chairman of Lifebox, an international not-for-profit that implements systems and technologies to reduce surgical deaths globally.
He has been a staff writer for The New Yorker since 1998. He has written three best-selling books: "Complications," which was a finalist for the National Book Award in 2002; "Better," which was selected as one of the ten best books of 2007 by Amazon.com; and "The Checklist Manifesto." He has won two National Magazine Awards, AcademyHealth’s Impact Award for the highest research impact on health care, and a MacArthur Fellowship, and he has been named one of the hundred most influential thinkers by Foreign Policy and Time."

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