Precision Medicine will need to get out of the pharma silo that is based on symptoms


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


After low-cost airlines (Ryanair, Easyjet ...) comes "low-cost" participatory medicine. Some of my readers have recently christened this long-lasting, clumsy attempt at e-writing of mine "THE LOW-COSTE INNOVATION BLOG". I am an
early adopter of scientific MOOCs. My name's Catherine Coste. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs?

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


APE Paperback edition coming NOW!

My favorite book on self-publishing.  If you're serious about self-publishing, you have to read it!
In five hours Amazon will start selling the paperback edition of APE. Now both Guy Kawasaki's artisanal-published books are in print. You can order APE here:

http://amzn.to/APE-DeadTreeEdition

There are 199 Amazon reviews for it: 176 five stars, 21 four stars, and 2 three stars which averages to five stars!

http://amzn.to/T37r5x

Here are three of the blurbs:
"Nuts, bolts, and inspiration too. Once again, Guy delivers, kicking the shiitake out of anyone who would tell you that you shouldn’t, wouldn’t or couldn’t write a book." 

Seth Godin, author and founder of The Icarus Project.
"Guy’s book is the perfect companion on the journey of independent publishing and great reading for the millions who aspire to become authors." 

Atif Rafiq, General Manager, Kindle Direct Publishing at Amazon.com
"APE is easily the most comprehensive, best organized, nuts-and-bolts-useful work on self-publishing I’ve seen to date. I think Guy has written the bible on self-publishing, and I expect it will be recognized—and widely used—as such." 

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