Scientific MOOCs follower. Author of Airpocalypse, a techno-medical thriller (Out Summer 2017)


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


I am an early adopter of scientific MOOCs. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs? Imagine all the people sharing their data...

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


Fashion business: a niche eco label founded by rock'n roll stars to help lift Africa out of poverty!

The 53 Nations of Africa have way too small a share of the world's trade: just 3% for 2010. Producing in that vast continent went at least some way to levelling that inequity... The brand is EDUN Americas and its mantra is compelling: "We carry the story of the people who make our clothes around with us."

An eco brand, that is, a sustainable, ethical luxury brand very much captures the "Zeitgeist" (especially in NY). What's behind the lofty or grand purpose, exactly? Janice Sullivan, CEO of EDUN, explains...

A piece by Marion Hume, fashion and travel journalist.

"As if the fashion business is not tough enough, Janice Sullivan must also meet Bono and Ali Hewson’s lofty aims for a niche eco label they founded to help lift Africa out of poverty.

There are times when I’m sitting with a Chief executive, who is completely ‘on message’, brilliant at expressing the ‘pillars’ of the brand and at talking through an impressive bottom line, yet I’m thinking, 'Yes, but you could be selling paint.' There are other times – rarer these – when I meet a CEO who is perhaps more tentative at first, yet utterly equipped for the unique challenges of the fashion business. A latter case is Janice Sullivan. As she puts it herself, 'I come from the back room. I’m hands on. I am all about product.'
Sullivan, an immaculate New York honey blonde in her mid 40s, does not have an expensive MBA. Instead, she has a roll-up-your-sleeves understanding of the logistics of making clothes and accessories in any part of the world. She knows her fabrics; she can tell at a glance how many you can cut of this and how long it is going to take to add beading.
'I started out in production; [was] then in product development; then in merchandising, then took over sales,' says Sullivan, who grew up on the Jersey shore looking across to Manhattan and whose career in New York City, until 18 months ago, involved switching back and forth between Calvin Klein and Donna Karan as she climbed the ladder at two iconic America brands. She was president of Calvin Klein Jeans when Mark Weber, who helms the LVMH business in the US, (which these days includes Donna Karan), asked her to take on a considerable challenge. She is now the CEO of Edun."


"In contrast to her past employers, Edun is a minnow; a niche eco brand where the numbers for an item might be 200, rather than 20,000, even 200,000 at Calvin Klein. Since 2009, this eco brand has been 49% owned by the luxury giant LVMH. You will certainly have heard of the pair who founded it in 2005, given they are rock star Bono and his wife, Ali Hewson.
To begin with, Edun received spectacular press, way more than the usual start-up because the world’s media was keen to get up close with Mr. & Mrs. Hewson. Edun garnered renown as the go-to made in Africa label (this even though the majority of product was sourced in Turkey, India, Peru). The mission became the message; that the 53 nations of Africa have way too small a share of the world’s trade (just 3% for 2010) and that producing in that vast continent went at least some way to levelling that inequity.
Ali Hewson, a political science graduate, proved every bit as forceful as her husband at delivering facts and figures about poverty, the numbers of people in sub-Saharan nations decimated by HIV/AIDS and how buying clothes could help. The brand’s mantra, 'We carry the story of the people who make our clothes around with us,' was compelling. But while the fashion business worships at the altar of celebrity if that is going to shift stuff, it is neither charitable nor forgiving. Late deliveries, inconsistent quality and lacklustre clothing lead retailers, initially so enthusiastic, to drop the line. It has been reported that the Hewsons pumped US$20 million of their own cash into Edun to keep it afloat while they shopped for an expert partner. LVMH acquired its stake for US$7.8 million.
While the timing was great for Edun, it was also good for LVMH, whose arch rival, PPR/Gucci Group, includes Stella McCartney, a brand that has moved from being perceived as, 'the awkward [run] one, by [an] animal rights activist who won’t use fish glue, let alone leather', to a sustainable, ethical, luxury brand that chimes precisely with the zeitgeist. LVMH needed an eco brand and to get one that could promise rockstar power to the front row (just as the daughter of Paul McCartney can) cannot but have added to the appeal.
The acquisition seemed the signal good times ahead. Sullivan was appointed to steer the brand; Sharon Wauchob, an Irish designer based in Paris, was hired to create a laid-back, modern fashion signature. (As to Wauchob’s nationality, she made clear on the first time we spoke that, 'Not everyone Irish knows Bono'. She got the gig based on her achievements, having never before met the Hewsons). LVMH brought business expertise: the ability to help a small company with IT, customs clearance and such like.
Then Bono and Ali Hewson followed the likes of Catherine Deneuve, Keith Richards and Mikhail Gorbachev by appearing in a 'Core Values' Louis Vuitton advertising campaign, which also name-checked Edun. Invites went out to a glamourous party to fete the collaboration and to showcase a Louis Vuitton “Keepall” bag,  featuring a slick cow horn charm, made by an Edun supplier in the slums of Nairobi. Profits from the bag, as well as the Hewsons’ fees, went to African causes.
Yet not for nothing is there an old saying, 'The road to hell is paved with good intentions'. Last September, The Wall Street Journal came out with a damning article headlined  'Out of Africa, Into Asia', containing the revelation that, since joining with LVMH, most of Edun’s clothes are made not by the poor of Africa but in highly mechanised factories in China. The story went round the world.
The WSJ piece was fair (the online version has a few clarifications, but no significant corrections), yet the ramifications of it have been unfortunate. While I was working on this piece, a leading style journalist mentioned she was working on a piece about producing in Africa but 'not featuring Edun; they make everything in China.' (To clarify further on the goods that are made in China, this is no longer synonymous with sweatshops; LVMH has stringent codes of compliance for its factory partners).
There were further reasons the WSJ story, its contents cherry picked and reprinted by global tabloids, garnered such traction. Some of this was due to Bono bashing, given he is a divisive figure. Some of it was due to a rare chink in the otherwise impregnable armour of the mighty LVMH (which is rarely criticised and also spends enormous amounts of money in the media advertising its brands).
'I think it is unfortunate some people put a lock on the brand,' says Janice Sullivan carefully. However she then acknowledges, 'because of all the press, because of Bono, there was a high level of expectation to not only have a beautiful collection, but to tick all these boxes in terms of sustainability, in terms of where things are made.
'But I think to go forward, you take it carefully and make sure you deliver. You want to make sure you have controlled growth. Our commitment is to make sure we grow the percentage of our line that we produce out of Africa. But it will never be everything.'
Depending how you cut it, 41% of Edun’s production is currently Africa, however this includes the Edun Live line of blank T-shirts, which are bulk-purchased by bands and brands as tour merchandise and are separate from the fashion offer. Also wrapped into that African percentage are items made in Morocco and Tunisia- North African nations that, (Tunisia’s current political turmoil not withstanding), are industrial suppliers to legions of fashion companies.
On the plus side and perhaps galvanised by press scrutiny, Edun has pledged that its fashion sourcing in the poverty belt of sub-Saharan Africa will rise to over 60%  by 2013. The highly visible fashion portion which started out as 15% of the collection, is expected to expand to 40%, and with steady attention, each collection should benefit from the transfer of skills needed to achieve these goals. Already, new collaborations are being forged; with The Crochet Sisters, a sisterhood of nuns and young girls, many of them refugees from Zimbabwe, who live and work in a safe environment in Nairobi; with a small company in Cameroon making sneakers and ongoing, with MADE, the Nairobi accessory company that provided the charm on the Vuitton Keepall bag.
Janice Sullivan is a realist. 'This is made in Asia,' she says, fingering a fluid silk dress that wraps and ties over the body. 'The fabrics are most likely Asian. These are African' she says, pointing to beads of recycled copper adorning a handknit. 'I think Edun can be the next big brand but in a different type of way. But right now, it’s about getting it right so we can grow.' Desirability and reliability have to come before any mission.'You can have a great story, but your product has to deliver, it has to be desired by people, it has to be right and on time. And you have to do it over and over again.'
Those who frame Edun’s  sourcing of the majority of its offer outside of Africa as some kind of ongoing failure lack an understanding of the logistics that Sullivan is talking about or of the challenges of producing in the sub-Saharan region, home to some of the most disadvantaged people on earth. 'As we grow more confident, we will expand our capacity in Africa,' Sullivan says. 'But I don’t want to overburden, overwhelm. I want to make sure we concentrate on good, strong pieces we know we can execute, and get them done.'
'Overburden' 'Overwhelm' are well chosen words. The challenges of producing in the developing world are legion. I know of this because I serve as a consultant to the UN agency, the International Trade Centre, on its global Ethical Fashion Programme, which encourages top designers to consider marginalized community producers among their suppliers. (Edun is not currently involved with the programme).
As you can imagine, it is not easy to produce high fashion in a Kenyan slum where the population density is 23 times that of Manhattan; neither is it so in war-torn rural Uganda where there are almost two million ‘Internally Displaced Persons’, refugees in their own land because of 20 years of civil war. Add to these, such externalities as lack of a reliable power supply and the need to get workers, especially women, home before dark, (which mitigating against the possibility of overtime).
It is surprisingly expensive to source among the poor. Just one equation; in Laos, one of the poorest countries in Asia, water and education are provided free by the communist regime, meaning the living wage is $3 a day. In Kenya, slum dwellers must pay even for access to drinking water, meaning their living wage is $4 a day – that extra dollar at source significantly upping the end price of a product. Currently Edun sources in Kenya, Uganda, Tanzania, Madagascar and the West African nation of Cameroon.
But one would safely assume that an ethical brand like Edun would be 100% organic, wherever it was producing, right? Wrong. Pesticides kill some 20,000 cotton growers a year from accidental poisoning, while a further million suffer ill health, according to Pesticide Action Network. This is compounded by the devastating effect on the environment. Edun has a noble commitment to organic cotton and has been a key force in the establishment of The Conservation Cotton Initiative (CCI) which enables displaced farmers in Northern Uganda to get the tools and funding they need to return to their land.
Appearance fees donated by Bono and Ali Hewson in the Annie Leibovitz-shot Core Values campaign were donated to CCI  facilitating the hiring of TechnoServe, a specialist in rural enterprise, The result has been that the number of farmers being helped has risen from 800 to 3,500, (the target is 8000).  Last season, Edun purchased 15 tonnes of this cotton, enough to make some 10,000 T shirts. 'We use organic materials whenever possible,' Sullivan said last year, 'but it’s not easy'.
Things just got harder- 2011 is an election year in Uganda and President Museveni is distributing free pesticides to farmers. 'We’ve decided to push a people agenda rather than the organic agenda,' says a sanguine Sullivan now. 'We’ve switched our efforts to teach responsible farming and how pesticides can be used sparingly. Yet she remains upbeat. 'These are the kind of complications Edun is willing to embrace in order to thrive and grow. Inconveniences are not insurmountable. They require patience but that pays off if the result is something special.'
Sullivan, a working mother of 15 year old twins, who is also stepmom to her husband’s 15 year old son, says she was ready for a new kind of fashion challenge. She is glad Edun is about forging long relationships around the world. But for Edun to fly, the clothes have to be great. While designer Wauchob has made as many visits to East Africa as she has been able (she has a young baby), she has resisted offering African styles or prints, choosing instead to use her time there researching what it is possible to make.
Hence black crochet skirts, little fringed vests, which are bang 'on trend' while the offer sourced elsewhere includes utilitarian parkas (wise, given winters seem to be getting harsher in the Northern Hemisphere fashion cities), snug chunky knits, floaty-long woven skirts and reconstructed Fair Isle patterns in rich earth tones. In other words, clothes that are not chasing youth but can be worn by grown up women such as Hewson, whose style signature is 'great pants, layers and a good jacket' and Sullivan, who needs to look like she means business, but not to look 'corporate'.
Sullivan is quick to praise the founders. 'A lot of great ideas come from those outside the industry…What appealed to me [when I joined] was the idea that we’re all in one world now, and you can’t remove yourself from the process any more. Fashion is a big influencer. I’ve worked for some very big brands. This is still a small brand but I think it has a lot of power.'
Certainly, there is no way Edun could have come so far, so fast without the Hewsons, who remain very much involved. 'I’m incredible impressed with how extensively they had already made in-roads, particularly in Uganda. It made my job a lot easier stepping in,' says Sullivan.
Star power continues to create magic. While last season, Sullivan apparently had to reign in Bono’s ambitions for a fashion extravaganza, telling him, 'We are having a fashion show. Show is the second word. Fashion is the first word.' This season, he’s helped to lift menswear sales by wearing Edun, as has fellow band member The Edge, during U2′s South African tour.  As for womenswear, REM’s Michael Stipe, Hugh Jackman, Helena Christensen and Christy Turlington sat in the front row at the New York show in February.
But neither a sprinkling of stardust or a good heart is enough in the tough business of fashion. 'It’s got to be great. No one cuts you slack. I can’t put out something that looks half way, there’s no such thing as ‘we’re almost there’,' says Sullivan. 'It’s always about what I can show you now that’s great.' She pauses. 'Take those black skirts made by the Crochet Sisters. We’ll do 600 of the skirts,  400 of the fringed vests. No, make that 2,000 units, I’m sure we’ll do that.'
And with just 2000 units – not 20,000, not 200,000 -  a community of women, many of whom have fled the violence of war to find unlikely sanctuary on the edge of one of the most dangerous slums in the world can work, eat and stay safe until next season’s order arrives." (Source).

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