In-gene-ious: Fixing a body’s broken genes is becoming possible http://t.co/iDiM6yqkJB #genomics Not so fast.... @TheEconomist
— Eric Topol (@EricTopol) February 6, 2014
http://www.economist.com/news/science-and-technology/21595888-fixing-bodys-broken-genes-becoming-possible-ingenious |
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"CRISPR-Cas9 editing is specific to particular sequences of genetic letters, and can thus be tweaked to do a researcher’s bidding. In a recent edition of Cell, Sha Jiahao of Nanjing Medical University showed how to use it to execute the reverse of gene therapy—creating genetic problems, rather than solving them—in monkeys. His aim was to produce model organisms that might help understanding of diseases in human beings (though making such models out of monkeys is controversial). But the technique might eventually be employed to do running repairs on damaged DNA in people. (...) For patients, that suggests gene therapy really is something worth fighting over."
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