Scientific MOOCs follower. Author of Airpocalypse, a techno-medical thriller (Out Summer 2017)


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


I am an early adopter of scientific MOOCs. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs? Imagine all the people sharing their data...

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


Affichage des articles dont le libellé est BREAST CANCER. Afficher tous les articles
Affichage des articles dont le libellé est BREAST CANCER. Afficher tous les articles

"Humankindness", Human Longevity and the "BRCA Commons" Theory

Paintress Regina Holliday is the founder of . She just posted her last work on Facebook, with these words:
I finished the Stanford Medicine X 2014 painting "All for one and One for all."

https://twitter.com/ReginaHolliday

Let's illustrate this with words, shall we?
http://www.bravebosom.com/we-need-a-brca-commons/
 "We Need A BRCA Commons," by Brave Bosom.

Thank you for this "Science and Society" manifesto, Brave Bosom! Everyone interested in genomics should read it!...


Cancer clinical trials reinvented

"Screening and some types of medical care are now articles of faith that science cannot overcome."

"(...) And then there is this sobering review article in Circulation entitled, Cancer Therapy–Induced Cardiac Toxicity in Early Breast Cancer Addressing the Unresolved Issues.  The vastness of that review article, and the fact that we have created an entire branch of cardiology to deal with medically-induced heart disease, makes you think hard about early treatment of anything.
This is important stuff. It’s not intended as anti-mammography or anti-chemotherapy.
It’s intended to make us all think about the tradeoffs of doing stuff."


Ready for a deep dive? Let's dive right in!

"The cumulative mortality from breast cancer is similar between women in the mammography arm and in the control arm."

"The cumulative mortality from breast cancer was similar between women in the mammography arm and in the control arm (hazard ratio 0.99, 95% confidence interval 0.88 to 1.12). After 15 years of follow-up a residual excess of 106 cancers was observed in the mammography arm, attributable to over-diagnosis."


Biologist Andy Ewald explains how breast cancer cells spread, using Play-Doh

Awesome! Just what we've learned at MIT 7.00x MOOC "The Secret of Life", Prof/Instructor: Eric Lander PhD -- minus the Play-Doh!