Scientific MOOCs follower. Author of Airpocalypse, a techno-medical thriller (Out Summer 2017)


Welcome to the digital era of biology (and to this modest blog I started in early 2005).

To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!


Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.


I am an early adopter of scientific MOOCs. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.

Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).

I love Genomics. Would you rather donate your data, or... your vital organs? Imagine all the people sharing their data...

Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.

Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).


Affichage des articles dont le libellé est BIG PHARMA. Afficher tous les articles
Affichage des articles dont le libellé est BIG PHARMA. Afficher tous les articles

The Pharma-Hollywood Congruence

http://bigbangtheory.wikia.com/wiki/The_Locomotion_Interruption
Bernadette: "OK. One more time. We throw chemotherapies blindly at cancer patients, which means we do not care about their genomic profile. The reason for this: whole genome sequencing is not yet a blockbuster."

Penny: "Why would we throw pills at the problem if it doesn't work?"

Bernadette: "Think of them as blockbusters, not as pills. In 'Big Pharma', B stands for Blockbuster: the one and only drug that will cover management's salaries and a whole variety of expenses like gourmet buffet dinners, posh golf clubs, nice congress venues worldwide, entertainment for the physicians. Last but not least, your salary and mine."

Penny: "Yeah, but those blockbusters you are talking about... Can they cure people?"

Bernadette: "Sometimes they can do that. The only thing that is 100% of the time true is that they are so damn expensive."

Penny: "Do people get a refund if the treatment doesn't work for them?"

Bernadette: "Now I need you to think very carefully. Criticizing a blockbuster can get you in real trouble. What would you like better? A well-paid job or death threats?"

Penny: "Got it. Big Pharma is just another Hollywood, with drugs instead of movies. This new job means I will pursue a new career in acting. Blockbuster? I'm all for it."

Bernadette: "Excellent. You are making the right choice."

How can we create a pipeline of MOOC candidates for biotechs & biopharma?



My question...







#LEXNYB (Twitter)

"New drug delivery system prevents transplant rejection"

"A life science recruiter's blog on placing R&D professionals"



Patents Or Patients? Big Pharma Has the Answer

Pig Pharma?...

" Genentech signs five-year collaboration with Patients Like Me for patient data"


"Big Data, Genetics and Translation"

http://genomeinformatician.blogspot.co.uk/2014/03/big-data-genetics-and-translation.html

"Drugs act on these targets. Drugs are often small molecules and sometimes proteins, like antibodies, that will change the activity of a biological target. A drug has to be able to enter the body, do what it was designed to do and not mess around doing other things. Pharmaceutical companies are really good at making these.
Clinical trials involve giving a new (or repurposed) drug to a group of consenting people. They are jaw-droppingly expensive. Unfortunately, the vast majority (90%) of drugs ultimately fail to make it through clinical trials. A large proportion of those fail because the information on which they were based, from right at the start – the target protein– was not quite right.
What’s the problem? In short, it is that a billion-dollar phase III clinical trial is a very expensive way to discover that your drug wasn't changing the right target."

Proudly Following Futuristech Info


Novel method produces molecules designed from RNA sequence to create new drugs

Le Franco'fil américain pour les biotechnologies françaises : The French BioBeach à San Diego

Stéphane Richard, président et fondateur de FrenchBioBeach, présente son organisation dont la mission est d'aider les bioentrepreneurs français qui souhaitent développer leurs affaires dans la région de San Diego. Business plan, installation...

http://blog.biotech-finances.com/audio-frenchbiobeach-san-diego-fait-le-pont-la-france-les-us/