She’s gone after pharma giants and governments. Meet @bmj_latest's editor: https://t.co/Nn07qlRIoZ pic.twitter.com/T9VNtdOUp8
— STAT (@statnews) January 9, 2016
Scientific MOOCs follower. Author of Airpocalypse, a techno-medical thriller (Out Summer 2017)
Welcome to the digital era of biology (and to this modest blog I started in early 2005).
To cure many diseases, like cancer or cystic fibrosis, we will need to target genes (mutations, for ex.), not organs! I am convinced that the future of replacement medicine (organ transplant) is genomics (the science of the human genome). In 10 years we will be replacing (modifying) genes; not organs!
Anticipating the $100 genome era and the P4™ medicine revolution. P4 Medicine (Predictive, Personalized, Preventive, & Participatory): Catalyzing a Revolution from Reactive to Proactive Medicine.
I am an early adopter of scientific MOOCs. I've earned myself four MIT digital diplomas: 7.00x, 7.28x1, 7.28.x2 and 7QBWx. Instructor of 7.00x: Eric Lander PhD.
Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).
I love Genomics. Would you rather donate your data, or... your vital organs? Imagine all the people sharing their data...
Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.
Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).
Upcoming books: Airpocalypse, a medical thriller (action taking place in Beijing) 2017; Jesus CRISPR Superstar, a sci-fi -- French title: La Passion du CRISPR (2018).
I love Genomics. Would you rather donate your data, or... your vital organs? Imagine all the people sharing their data...
Audio files on this blog are Windows files ; if you have a Mac, you might want to use VLC (http://www.videolan.org) to read them.
Concernant les fichiers son ou audio (audio files) sur ce blog : ce sont des fichiers Windows ; pour les lire sur Mac, il faut les ouvrir avec VLC (http://www.videolan.org).
Affichage des articles dont le libellé est BIG PHARMA. Afficher tous les articles
Affichage des articles dont le libellé est BIG PHARMA. Afficher tous les articles
"The entire ecosystem of drug evaluation and regulation is deeply flawed"
The Pharma-Hollywood Congruence
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| http://bigbangtheory.wikia.com/wiki/The_Locomotion_Interruption |
Penny: "Why would we throw pills at the problem if it doesn't work?"
Bernadette: "Think of them as blockbusters, not as pills. In 'Big Pharma', B stands for Blockbuster: the one and only drug that will cover management's salaries and a whole variety of expenses like gourmet buffet dinners, posh golf clubs, nice congress venues worldwide, entertainment for the physicians. Last but not least, your salary and mine."
Penny: "Yeah, but those blockbusters you are talking about... Can they cure people?"
Bernadette: "Sometimes they can do that. The only thing that is 100% of the time true is that they are so damn expensive."
Penny: "Do people get a refund if the treatment doesn't work for them?"
Bernadette: "Now I need you to think very carefully. Criticizing a blockbuster can get you in real trouble. What would you like better? A well-paid job or death threats?"
Penny: "Got it. Big Pharma is just another Hollywood, with drugs instead of movies. This new job means I will pursue a new career in acting. Blockbuster? I'm all for it."
Bernadette: "Excellent. You are making the right choice."
Coin Wishing Tree, Big Pharma And The Inverse Dynamics Theory
Coin Wishing Tree in UK cc @paradox_doctor https://t.co/4x03J5dIEp #BigPharma working the other way around today :-) pic.twitter.com/IfptcORSFy
— CATHERINE COSTE (@cathcoste) November 18, 2015
How can we create a pipeline of MOOC candidates for biotechs & biopharma?
Modern American Medical Education at a Crossroads: #PrecisionMedicine #bioinformatics #translation #outcomes #PWSYN http://t.co/z3eDJzSPw3
— Dr. Muin Khoury (@DrKhouryCDC) April 30, 2015
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How can we create a pipeline of #MOOC candidates for biotechs & biopharma? http://t.co/ipa2uOgRGh @eric_lander #700x pic.twitter.com/x73vlIGhJ4
— CATHERINE COSTE (@cathcoste) April 30, 2015
I'll be looking forward to having the opportunity to discuss the role of #MOOCs in medical education, both for patients & for doctors #PWSYN
— CATHERINE COSTE (@cathcoste) April 30, 2015
— Helene Allaire (@HeleneON) April 30, 2015
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| #LEXNYB (Twitter) |
.@endnilsson @eric_lander #MOOC for dummies = gr8 idea indeed. Bringing the knowledge of #genomics 2 dummies like me -> ticket for the Big N
— CATHERINE COSTE (@cathcoste) May 1, 2015
Big Pharma Turning New Cancer Treatment Into Highly Profitable Niche
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| http://online.wsj.com/articles/new-costly-cancer-treatments-face-hurdles-getting-to-patients-1412627150 |
Cost of #cancer drugs--theme of the week @60Minutes @Health_Affairs and @WSJ http://t.co/hjWae22MyJ pic.twitter.com/9Tqq63Acng
— Eric Topol (@EricTopol) October 7, 2014
"Peter Thiel's Uncomplementary Views of Big Pharma"
Agree! RT @cathcoste: Peter Thiel's Uncomplementary Views of Big Pharma via @Dereklowe http://t.co/e6DAUOiZ42 pic.twitter.com/dfURQ9lZ9n
— Robert West PhD (@westr) September 23, 2014
"New drug delivery system prevents transplant rejection"
New drug delivery system prevents transplant rejection http://t.co/7dOMBvqe6i
— Harvard University (@Harvard) August 13, 2014
Brigham and Women’s develops gel that could make limb transplants more successful http://t.co/yzroTXDCRm via @BostonBizNews
— David R. Bachinsky (@drbachinsky) August 14, 2014
"A life science recruiter's blog on placing R&D professionals"
.@Clarksearch "Any consideration 4 opportunity cost of letting a position sit empty while lots of time spent on finding perfect candidate?"
— CATHERINE COSTE (@cathcoste) August 7, 2014
What are life science job candidates supposed 2 do 2 navigate "algorithm-driven minefield?" http://t.co/rkv85sbW29 @Xconomy via @Clarksearch
— CATHERINE COSTE (@cathcoste) August 7, 2014
"There's no... law that says jobs eliminated by new tech will inevitably be replaced by new jobs in new markets…
http://t.co/Z8CRwt9HoS
— Jason Pontin (@jason_pontin) August 6, 2014
Big Data in Big Pharma = Big Bucks Minus Vital Data -- Why "minus"? This doesn't add up.
Boehringer Ingelheim put lives at risk by withholding vital data. Business as usual for modern medicine #AllTrials http://t.co/UCincU47IP
— ben goldacre (@bengoldacre) July 24, 2014
Hacking Pharma...
Patents Or Patients? Big Pharma Has the Answer
“At Pfizer, PATENTS always come 1rst. Our primary goal is,& always will be, keeping them alive & healthy (...)" http://t.co/5V5pkKzbny #CDoM
— CATHERINE COSTE (@cathcoste) July 12, 2014
Pig Pharma?... " Genentech signs five-year collaboration with Patients Like Me for patient data"
We are excited to enter patient-centric research collaboration with @PatientsLikeMe http://t.co/FICWMRF4E0
— Genentech (@genentech) April 7, 2014
Wonder how pats will feel? RT @matthewherper: Genentech signs five-year collaboration with @patientslikeme for patient data. Interesting.
— Sally Church (@MaverickNY) April 7, 2014
"Big Data, Genetics and Translation"
I’ll be following @ewanbirney et al’s foray into drug target validation with great interest: http://t.co/XMpDPCElLC
— Daniel MacArthur (@dgmacarthur) March 27, 2014
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| http://genomeinformatician.blogspot.co.uk/2014/03/big-data-genetics-and-translation.html |
"Drugs act on these targets. Drugs are often
small molecules and sometimes proteins, like antibodies, that will change the
activity of a biological target. A drug has to be able to enter the body, do
what it was designed to do and not mess around doing other things. Pharmaceutical
companies are really good at making these.
Clinical trials
involve giving a new (or repurposed) drug to a group of consenting people. They
are jaw-droppingly expensive. Unfortunately, the vast majority (90%) of drugs
ultimately fail to make it through clinical trials. A large proportion of those
fail because the information on which they were based, from right at the start – the target protein– was
not quite right.
What’s the
problem? In short, it is that a billion-dollar phase III clinical trial is a
very expensive way to discover that your drug wasn't changing the right target."
How Social Media and Big Data are Changing the Landscape of Surveillance and Research
How Social Media and Big Data are Changing the Landscape of Surveillance and Research http://t.co/5mrMDJsNbo
— CATHERINE COSTE (@cathcoste) February 14, 2014
38,000 fatal drug overdoses a year in the US
38,000 fatal drug overdoses a year in the US http://t.co/BPP0ZkTLLR Here’s the guy in charge of helping fix that http://t.co/xaGXFlRFSe
— ben goldacre (@bengoldacre) February 11, 2014
Novel method produces molecules designed from RNA sequence to create new drugs
Novel method produces molecules designed from RNA sequence to create new drugs
http://t.co/BlU3I9ow1o pic.twitter.com/sc2iMeyIYu
— FUTURISTECH INFO (@FuturistechInfo) February 9, 2014
Le Franco'fil américain pour les biotechnologies françaises : The French BioBeach à San Diego
Stéphane Richard, président et fondateur de FrenchBioBeach, présente son
organisation dont la mission est d'aider les bioentrepreneurs français
qui souhaitent développer leurs affaires dans la région de San Diego.
Business plan, installation...
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| http://blog.biotech-finances.com/audio-frenchbiobeach-san-diego-fait-le-pont-la-france-les-us/ |
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