Genome editing monkeys->Gene Rx humans? http://t.co/uWXU0k4uiY @CellCellPress http://t.co/eYlLdL7X3I @sciencemagazine pic.twitter.com/z5K3Nl2zwd
— Eric Topol (@EricTopol) January 30, 2014
"Using a recently developed genome-editing technique called CRISPR, a
Chinese team has successfully altered two target genes
in cynomolgus monkeys, paving the way for the
development of monkey models that mimic human diseases. This is the
first evidence
that CRISPR can work in primates and represents a
big advance over previous successes in genetically modifying monkeys,
in
which genes were inserted randomly into the
genome. Only two of the three target genes were modified, and not all
cells carry
the same modification, indicating more work
needs to be done to perfect the timing of the modification. Beyond its
significance
for biomedical research, the new work raises the
possibility that CRISPR will one day be used to change the genetic
makeup
of human embryos."
"CRISPR will one day be used to change the genetic makeup of human embryos."
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